Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.37 |
| ▸ | XDH | P47989 | 1/20 | 0.36 |
| ▸ | MGLL | Q99685 | 1/20 | 0.35 |
| ▸ | SOS1 | Q07889 | 2/20 | 0.34 |
| ▸ | TTR | P02766 | 1/20 | 0.33 |
| ▸ | ALB | P02768 | 1/20 | 0.33 |
| ▸ | GRM5 | P41594 | 3/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23526347 | 1.00 | ALDH1A1 (0.37) | ALDH1A1CYP2A6XDHMGLLSOS1 | |
| SCHEMBL10204233 | 0.83 | ALDH1A1 (0.39) | ALDH1A1CYP2A6XDHMGLLSOS1 | |
| SCHEMBL16955395 | 0.80 | ALDH1A1 (0.37) | ALDH1A1CYP2A6XDHMGLLSOS1 | |
| SCHEMBL7358313 | 0.80 | ALDH1A1 (0.37) | ALDH1A1CYP2A6XDHMGLLSOS1 | |
| SCHEMBL25628413 | 0.79 | SOS1 (0.39) | ALDH1A1CYP2A6XDHMGLLSOS1 | |
| SCHEMBL23525975 | 0.78 | GRM5 (0.36) | MGLLSOS1GRM5 | |
| SCHEMBL23525972 | 0.78 | GRM5 (0.36) | MGLLSOS1GRM5 | |
| SCHEMBL29945798 | 0.78 | GRM5 (0.36) | MGLLSOS1GRM5 | |
| Hydrochloric Acid SCHEMBL30496907 | 0.78 | TTR (0.32) | ALDH1A1TTRALB | |
| Hydrochloric Acid SCHEMBL26628819 | 0.78 | TTR (0.32) | ALDH1A1TTRALB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119462626-A | SOS1 inhibitors | 米拉蒂治疗股份有限公司 | 2025-02-18 | — | — | CN | disclosed |
| CN-115135315-B | SOS1 inhibitors | 米拉蒂治疗股份有限公司 | 2024-11-26 | — | — | CN | disclosed |
| EP-4076418-A1 | SOS1 INHIBITORS | Mirati Therapeutics, Inc. (US) | 2022-10-26 | — | — | EP | disclosed |
| CN-115135315-A | SOS1 inhibitors | 米拉蒂治疗股份有限公司 | 2022-09-30 | — | — | CN | disclosed |