Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 1/20 | 0.41 |
| ▸ | AR | P10275 | 14/20 | 0.40 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2134651 | 1.00 | DYRK1A (0.41) | DYRK1AARPDK2TSHRLMNA | |
| SCHEMBL25983090 | 0.85 | AR (0.46) | ARPDK2TSHRPGR | |
| SCHEMBL21718846 | 0.80 | DYRK1A (0.41) | DYRK1AARPDK2TSHRLMNA | |
| SCHEMBL23726465 | 0.78 | HCAR1 (0.40) | PDK2TSHRLMNAHCAR1 | |
| SCHEMBL1994873 | 0.78 | AR (0.41) | ARPDK2TSHRPGR | |
| SCHEMBL3911267 | 0.78 | AR (0.46) | ARPGR | |
| SCHEMBL29378798 | 0.78 | AR (0.41) | ARPDK2TSHRPGR | |
| SCHEMBL16960191 | 0.76 | AR (0.40) | ARPDK2TSHRPGR | |
| SCHEMBL14699104 | 0.76 | DYRK1A (0.42) | DYRK1AARPDK2TSHRPGR | |
| SCHEMBL5228912 | 0.76 | TSHR (0.54) | ARTSHRPGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4663626-A1 | IMINE COMPOUNDS AS WELL AS PREPARATION METHOD THEREFOR AND USE THEREOF | Bio Genuine (Shanghai) Biotech Co., Ltd (CN) | 2025-12-17 | — | — | EP | disclosed |
| CN-119546304-A | Salts of SOS1 inhibitors | 米拉蒂治疗公司 | 2025-02-28 | — | — | CN | disclosed |
| CN-119462626-A | SOS1 inhibitors | 米拉蒂治疗股份有限公司 | 2025-02-18 | — | — | CN | disclosed |
| CN-115135315-B | SOS1 inhibitors | 米拉蒂治疗股份有限公司 | 2024-11-26 | — | — | CN | disclosed |
| WO-2024165071-A1 | IMINE COMPOUNDS AS WELL AS PREPARATION METHOD THEREFOR AND USE THEREOF | 上海葆正医药科技有限公司 | 2024-08-15 | — | — | WO | disclosed |
| CN-115135315-A | SOS1 inhibitors | 米拉蒂治疗股份有限公司 | 2022-09-30 | — | — | CN | disclosed |