Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EED | O75530 | 7/20 | 0.40 |
| ▸ | SCN1A | P35498 | 1/20 | 0.38 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.38 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23526016 | 1.00 | EED (0.40) | EEDSCN1ASCN5ASCN8ATAAR1 | |
| SCHEMBL28879852 | 0.85 | TAAR1 (0.43) | TAAR1KDM4EMEN1KMT2ACYP3A4 | |
| SCHEMBL6072037 | 0.85 | TAAR1 (0.43) | TAAR1MCL1SMN1; SMN2KDM4EMEN1 | |
| Hydrochloric Acid SCHEMBL29210672 | 0.83 | KDM4E (0.44) | TAAR1MCL1SMN1; SMN2KDM4EMEN1 | |
| Hydrochloric Acid SCHEMBL31564653 | 0.78 | RXFP1 (0.38) | EEDSCN1ASCN5ASCN8ATAAR1 | |
| SCHEMBL6911041 | 0.78 | ALDH1A1 (0.44) | TAAR1KDM4EMEN1KMT2AGPR84 | |
| SCHEMBL14613959 | 0.78 | ACHE (0.44) | EEDSCN8ATAAR1MCL1SMN1; SMN2 | |
| SCHEMBL14144306 | 0.77 | EED (0.43) | EEDTAAR1SMN1; SMN2KDM4EMEN1 | |
| SCHEMBL31614296 | 0.77 | EED (0.43) | EEDTAAR1SMN1; SMN2KDM4EMEN1 | |
| SCHEMBL22362782 | 0.77 | NPSR1 (0.46) | SMN1; SMN2KMT2ACYP3A4ALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4543450-A1 | SALTS OF SOS1 INHIBITORS | Mirati Therapeutics, Inc. (US) | 2025-04-30 | — | — | EP | disclosed |
| CN-119546304-A | Salts of SOS1 inhibitors | 米拉蒂治疗公司 | 2025-02-28 | — | — | CN | disclosed |
| CN-119462626-A | SOS1 inhibitors | 米拉蒂治疗股份有限公司 | 2025-02-18 | — | — | CN | disclosed |
| CN-115135315-B | SOS1 inhibitors | 米拉蒂治疗股份有限公司 | 2024-11-26 | — | — | CN | disclosed |
| WO-2023250165-A1 | SALTS OF SOS1 INHIBITORS | Mirati Therapeutics, Inc. (US) | 2023-12-28 | — | — | WO | disclosed |
| EP-4076418-A1 | SOS1 INHIBITORS | Mirati Therapeutics, Inc. (US) | 2022-10-26 | — | — | EP | disclosed |
| CN-115135315-A | SOS1 inhibitors | 米拉蒂治疗股份有限公司 | 2022-09-30 | — | — | CN | disclosed |