Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | GPR27 | Q9NS67 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23526480 | 1.00 | KMT2A (0.41) | KMT2ASOS1TSHRNPSR1LMNA | |
| SCHEMBL31394743 | 0.83 | SOS1 (0.51) | SOS1TSHRNPSR1LMNASIRT6 | |
| SCHEMBL24885565 | 0.78 | KDM4E (0.51) | KMT2ATSHRLMNAKDM4EHSD17B10 | |
| SCHEMBL23526138 | 0.77 | SOS1 (0.47) | SOS1TSHRNPSR1LMNASIRT6 | |
| SCHEMBL24801995 | 0.77 | SOS1 (0.47) | SOS1TSHRNPSR1LMNASIRT6 | |
| SCHEMBL29183380 | 0.77 | TSHR (0.44) | KMT2ATSHRNPSR1LMNAKDM4E | |
| SCHEMBL31559525 | 0.77 | NR4A2 (0.43) | KMT2ANPSR1LMNAKDM4EHSD17B10 | |
| SCHEMBL23526253 | 0.77 | NR4A2 (0.43) | KMT2ANPSR1LMNAKDM4EHSD17B10 | |
| SCHEMBL23526377 | 0.77 | ALOX5 (0.40) | KMT2ASOS1TSHRPKMKDM4E | |
| SCHEMBL29945784 | 0.77 | ALOX5 (0.40) | KMT2ASOS1TSHRPKMKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119462626-A | SOS1 inhibitors | 米拉蒂治疗股份有限公司 | 2025-02-18 | — | — | CN | disclosed |
| CN-115135315-B | SOS1 inhibitors | 米拉蒂治疗股份有限公司 | 2024-11-26 | — | — | CN | disclosed |
| CN-115135315-A | SOS1 inhibitors | 米拉蒂治疗股份有限公司 | 2022-09-30 | — | — | CN | disclosed |