Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | GABRA1 | P14867 | 7/20 | 0.43 |
| ▸ | GABRB2 | P47870 | 6/20 | 0.43 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.43 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.43 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11387344 | 0.84 | MAPK1 (0.64) | MAPK1GABRA1GABRB2CYP11B1CYP11B2 | |
| SCHEMBL24934519 | 0.78 | MAPK1 (0.57) | MAPK1GABRA1GABRB2CYP11B1CYP11B2 | |
| SCHEMBL10563331 | 0.77 | MAPK1 (0.50) | MAPK1GABRA1GABRB2CYP11B1CYP11B2 | |
| SCHEMBL10390462 | 0.76 | MAPK1 (0.75) | MAPK1GABRA1GABRB2CYP11B1CYP11B2 | |
| Hydrochloric Acid SCHEMBL29981865 | 0.76 | MAPK1 (0.59) | MAPK1GABRA1GABRB2CYP11B1CYP11B2 | |
| Hydrochloric Acid SCHEMBL11334431 | 0.75 | MAPK1 (0.78) | MAPK1GABRA1GABRB2CYP11B1CYP11B2 | |
| Metomidate SCHEMBL4377172 | 0.75 | MAPK1 (0.97) | MAPK1GABRA1GABRB2CYP11B1CYP11B2 | |
| SCHEMBL21097972 | 0.75 | MAPK1 (0.51) | MAPK1GABRA1GABRB2CYP11B1CYP11B2 | |
| Metomidate SCHEMBL491910 | 0.75 | MAPK1 (0.97) | MAPK1GABRA1GABRB2CYP11B1CYP11B2 | |
| SCHEMBL22004285 | 0.74 | MAPK1 (0.76) | MAPK1GABRA1GABRB2CYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022184849-A1 | GLP-1R AGONISTS, USES AND PHARMACEUTICAL COMPOSITIONS THEREOF | LES LABORATOIRES SERVIER (FR) | 2022-09-09 | — | — | WO | disclosed |