Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM5A | P29375 | 1/20 | 0.41 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.41 |
| ▸ | PTGER1 | P34995 | 5/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.41 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | CYP3A5 | P20815 | 2/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.39 |
| ▸ | HTR2C | P28335 | 2/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.39 |
| ▸ | GLP1R | P43220 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29945948 | 0.89 | MAOB (0.45) | KDM5AKDM5BPTGER1GPR119HTR2C | |
| SCHEMBL24265933 | 0.84 | GPR119 (0.42) | GPR119 | |
| SCHEMBL29573851 | 0.84 | GPR119 (0.42) | GPR119 | |
| SCHEMBL29945877 | 0.82 | GPR119 (0.43) | CYP3A4CYP3A5GPR119 | |
| SCHEMBL30468806 | 0.76 | GPR119 (0.46) | CYP3A4CYP3A5GPR119GLP1R | |
| SCHEMBL26913982 | 0.76 | GLP1R (0.51) | CYP3A4CYP3A5GPR119GLP1R | |
| SCHEMBL21438728 | 0.76 | BCHE (0.33) | GPR119 | |
| SCHEMBL20029774 | 0.75 | GPR119 (0.39) | GPR119 | |
| SCHEMBL31670786 | 0.75 | GLP1R (0.46) | CYP3A4CYP3A5GLP1R | |
| SCHEMBL24265552 | 0.75 | PKM (0.47) | PTGER1CYP2C9GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022184849-A1 | GLP-1R AGONISTS, USES AND PHARMACEUTICAL COMPOSITIONS THEREOF | LES LABORATOIRES SERVIER (FR) | 2022-09-09 | — | — | WO | disclosed |