Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | AGXT | P21549 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.35 |
| ▸ | DHFR | P00374 | 2/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL99339 | 0.70 | TSHR (0.41) | TSHRALDH1A1IDO1AGXTMAPK14 | |
| SCHEMBL369968 | 0.70 | HDAC3 (0.53) | TSHRPTGER1 | |
| SCHEMBL18577540 | 0.68 | CYP19A1 (0.48) | ALDH1A1 | |
| SCHEMBL4911096 | 0.67 | DHFR (0.40) | TSHRALDH1A1IDO1AGXTMAOB | |
| SCHEMBL3359631 | 0.66 | TSHR (0.44) | TSHRALDH1A1IDO1AGXTDHFR | |
| SCHEMBL4581854 | 0.66 | NOTUM (0.41) | TSHRALDH1A1IDO1AGXTDHFR | |
| SCHEMBL4916083 | 0.65 | ADORA2A (0.40) | TSHRALDH1A1IDO1AGXTMAOB | |
| SCHEMBL25418589 | 0.63 | TSHR (0.38) | TSHRALDH1A1IDO1AGXTDHFR | |
| SCHEMBL766418 | 0.62 | TSHR (0.57) | TSHRALDH1A1IDO1AGXTMAOB | |
| SCHEMBL28598923 | 0.62 | TSHR (0.50) | TSHRALDH1A1IDO1AGXT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022184849-A1 | GLP-1R AGONISTS, USES AND PHARMACEUTICAL COMPOSITIONS THEREOF | LES LABORATOIRES SERVIER (FR) | 2022-09-09 | — | — | WO | disclosed |