Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | DHFR | P00374 | 6/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | AGXT | P21549 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27939335 | 0.71 | ALDH1A1 (0.36) | TSHRHPGDKMT2AMEN1NPSR1 | |
| SCHEMBL9672155 | 0.68 | CYP11B1 (0.53) | TSHRHPGDKMT2AMEN1NPSR1 | |
| SCHEMBL27792150 | 0.67 | TSHR (0.50) | TSHRKMT2AALDH1A1IDO1L3MBTL1 | |
| SCHEMBL9304768 | 0.67 | CYP19A1 (0.58) | HPGDKMT2AMEN1ALDH1A1L3MBTL1 | |
| SCHEMBL28598923 | 0.67 | TSHR (0.50) | TSHRALDH1A1IDO1AGXTCYP1A2 | |
| SCHEMBL4581854 | 0.67 | NOTUM (0.41) | TSHRHPGDKMT2AMEN1NPSR1 | |
| SCHEMBL3269756 | 0.65 | ALDH1A1 (0.58) | TSHRHPGDKMT2AMEN1NPSR1 | |
| SCHEMBL223907 | 0.64 | TSHR (0.78) | TSHRALDH1A1IDO1AGXTKDM4E | |
| SCHEMBL99339 | 0.64 | TSHR (0.41) | TSHRALDH1A1DHFRIDO1AGXT | |
| SCHEMBL2982806 | 0.64 | TSHR (0.46) | TSHRALDH1A1DHFRIDO1AGXT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7655769-B2 | Orthogonally protected disaccharide building blocks for synthesis of heparin | ACADEMIA SINICA (TW) | 2010-02-02 | — | — | US | disclosed |
| US-7582737-B2 | Orthogonally protected disaccharide building blocks for synthesis of heparin oligosaccharides | ACADEMIA SINICA (TW) | 2009-09-01 | — | — | US | disclosed |
| US-20080171722-A1 | Heparin Oligosaccharides | ACADEMIA SINICA, OFFICE OF PUBLIC AFFAIRS (TECHNOLOGY TRANSFER) (TW) | 2008-07-17 | — | — | US | disclosed |
| US-20060079483-A1 | Heparin oligosaccharides | ACADEMIA SINICA (TW) | 2006-04-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080171722-A1 | Heparin Oligosaccharides | HPSE, FUT5, CSGALNACT1 | TSHR 2339/4885HPGD 759/4885KMT2A 3326/4885 |
| US-20060079483-A1 | Heparin oligosaccharides | HPSE, FUT5, CSGALNACT1 | TSHR 2339/4885HPGD 759/4885KMT2A 3326/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.