SCHEMBL29946133

SCHEMBL29946133

CC(C)C[C@H](N)C(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)N[C@H](C(=O)N[C@@H](C)C(=O)N[C@H](C=O)CC(=O)O)C(C)C

nearest known ligand 0.46

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ CALCRL Q16602 6/20 0.46
▸ XIAP P98170 2/20 0.44
▸ ELANE P08246 6/20 0.39
▸ RAMP1 O60894 1/20 0.39
▸ REN P00797 2/20 0.36
▸ ACE P12821 1/20 0.36
▸ MLX Q9UH92 1/20 0.36
▸ CAPN1 P07384 1/20 0.36
▸ CTSD P07339 1/20 0.35
▸ BACE1 P56817 1/20 0.35
▸ CASP1 P29466 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30657497 0.85 CALCRL (0.44) CALCRLELANERAMP1RENCAPN1
SCHEMBL21312750 0.82 XIAP (0.55) CALCRLXIAPELANERENACE
SCHEMBL30399601 0.81 ACE (0.45) RENACE
SCHEMBL5065490 0.81 XIAP (0.48) CALCRLXIAPELANERAMP1REN
SCHEMBL5065494 0.81 XIAP (0.48) CALCRLXIAPELANERAMP1REN
SCHEMBL29609081 0.80 CALCRL (0.46) CALCRLXIAPRENCAPN1CTSD
SCHEMBL29801921 0.80 CALCRL (0.51) CALCRLRAMP1CTSDBACE1
SCHEMBL30596283 0.79 CALCRL (0.45) CALCRLXIAPRENACEMLX
SCHEMBL31500765 0.78 CALCRL (0.51) CALCRLXIAPRAMP1CAPN1
SCHEMBL29521253 0.78 CALCRL (0.49) CALCRLXIAPRAMP1RENCAPN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250146050-A1 STABILISATION OF BIOLOGICAL SAMPLES QIAGEN GMBH (DE) 2025-05-08 — — US disclosed
US-20250122555-A1 STABILISATION OF BIOLOGICAL SAMPLES QIAGEN GMBH (DE) 2025-04-17 — — US disclosed
US-12139744-B2 Stabilisation of biological samples QIAGEN GMBH (DE) 2024-11-12 — — US disclosed
US-12110533-B2 Stabilisation and isolation of extracellular nucleic acids QIAGEN GMBH (DE) 2024-10-08 — — US disclosed
US-11525155-B2 Stabilisation of biological samples QIAGEN GMBH (DE) 2022-12-13 — — US disclosed
US-20220364149-A1 STABILISATION OF BIOLOGICAL SAMPLES QIAGEN GMBH (DE) 2022-11-17 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250122555-A1 STABILISATION OF BIOLOGICAL SAMPLES RNASE1, RNASEH1, EWSR1 CALCRL 3211/4885XIAP 1307/4885ELANE 204/4885
US-12139744-B2 Stabilisation of biological samples RNASE1, RNASEH1, EWSR1 CALCRL 3211/4885XIAP 1307/4885ELANE 204/4885
US-20250146050-A1 STABILISATION OF BIOLOGICAL SAMPLES RNASE1, RNASEH1, EWSR1 CALCRL 3211/4885XIAP 1307/4885ELANE 204/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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