Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCF1 | P14598 | 3/20 | 1.00 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.47 |
| ▸ | NOS2 | P35228 | 1/20 | 0.46 |
| ▸ | BACE1 | P56817 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | CNR2 | P34972 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31650826 | 1.00 | NCF1 (1.00) | NCF1CYP1A2HIF1ALMNAPTK2 | |
| SCHEMBL4263734 | 1.00 | NCF1 (1.00) | NCF1CYP1A2HIF1ALMNAPTK2 | |
| Quinoline SCHEMBL28116903 | 0.89 | NCF1 (0.79) | NCF1CYP1A2HIF1ALMNAPTK2 | |
| SCHEMBL12383278 | 0.86 | NCF1 (0.76) | NCF1CYP1A2HIF1ALMNAPTK2 | |
| SCHEMBL3644084 | 0.83 | NCF1 (0.70) | NCF1CYP1A2HIF1ALMNAPTK2 | |
| SCHEMBL12014904 | 0.81 | NCF1 (0.68) | NCF1CYP1A2HIF1ALMNAPTK2 | |
| SCHEMBL4556260 | 0.80 | NCF1 (0.65) | NCF1CYP1A2HIF1ALMNAPTK2 | |
| SCHEMBL13557858 | 0.79 | NCF1 (0.66) | NCF1CYP1A2HIF1ALMNAPTK2 | |
| SCHEMBL9279566 | 0.78 | NCF1 (0.63) | NCF1CYP1A2HIF1ALMNAPTK2 | |
| SCHEMBL13557868 | 0.78 | NCF1 (0.63) | NCF1CYP1A2HIF1ALMNAPTK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2586893-B1 | COPPER PLATING BATH AND CORRESPONDING METHOD | ROHM & HAAS ELECT MAT (US) | 2022-09-21 | — | — | EP | claimed |
| CN-119546572-A | Novel naphthyl and isoquinoline sulfonamide derivatives | 豪夫迈·罗氏有限公司 | 2025-02-28 | — | — | CN | disclosed |
| US-20240245673-A1 | Papain-like protease (PLpro) inhibitors | PFIZER INC. (US) | 2024-07-25 | — | — | US | disclosed |
| US-20240067632-A1 | WEE1 Degrading Compounds and Uses Thereof | BRISTOL-MYERS SQUIBB COMPANY (US) | 2024-02-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240245673-A1 | Papain-like protease (PLpro) inhibitors | PREP, PEPD, ACE | NCF1 3667/4885CYP1A2 831/4885HIF1A 1930/4885 |
| US-20240067632-A1 | WEE1 Degrading Compounds and Uses Thereof | WEE1, WEE2, PPME1 | NCF1 3197/4885CYP1A2 3456/4885HIF1A 1645/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.