Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 12/20 | 0.65 |
| ▸ | HSD17B10 | Q99714 | 9/20 | 0.65 |
| ▸ | HPGD | P15428 | 7/20 | 0.65 |
| ▸ | CYP1A2 | P05177 | 6/20 | 0.65 |
| ▸ | CYP2D6 | P10635 | 12/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 9/20 | 0.50 |
| ▸ | TSHR | P16473 | 8/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 6/20 | 0.50 |
| ▸ | USP2 | O75604 | 5/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.39 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.39 |
| ▸ | CDC42BPB | Q9Y5S2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL194151 | 0.78 | PLD1 (0.59) | ALDH1A1HSD17B10HPGDCYP1A2CYP2D6 | |
| SCHEMBL15863561 | 0.78 | PLD1 (0.59) | ALDH1A1HSD17B10HPGDCYP1A2CYP2D6 | |
| Hydrochloric Acid SCHEMBL4808448 | 0.76 | PLD1 (0.58) | ALDH1A1HSD17B10HPGDCYP1A2CYP2D6 | |
| Hydrochloric Acid SCHEMBL31394440 | 0.76 | PLD1 (0.58) | ALDH1A1HSD17B10HPGDCYP1A2CYP2D6 | |
| SCHEMBL13018665 | 0.75 | HRH3 (0.65) | ALDH1A1HSD17B10HPGDCYP1A2CYP2D6 | |
| SCHEMBL16430513 | 0.74 | ALDH1A1 (0.56) | ALDH1A1HSD17B10HPGDCYP1A2CYP2D6 | |
| SCHEMBL27226470 | 0.72 | ALDH1A1 (0.54) | ALDH1A1HSD17B10HPGDCYP1A2CYP2D6 | |
| SCHEMBL30663939 | 0.71 | ALDH1A1 (0.65) | ALDH1A1HSD17B10HPGDCYP1A2CYP2D6 | |
| SCHEMBL9767811 | 0.70 | — | — | |
| SCHEMBL31540828 | 0.70 | CYP1A2 (0.46) | ALDH1A1HSD17B10HPGDCYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4337203-A1 | INHIBITORS OF THE MENIN-MLL INTERACTION | Syndax Pharmaceuticals, Inc. (US) | 2024-03-20 | — | — | EP | disclosed |
| WO-2022241265-A1 | INHIBITORS OF THE MENIN-MLL INTERACTION | SYNDAX PHARMACEUTICALS, INC. (US) | 2022-11-17 | — | — | WO | disclosed |