Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPE | Q05469 | 8/20 | 0.49 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.48 |
| ▸ | HCRTR1 | O43613 | 8/20 | 0.45 |
| ▸ | HCRTR2 | O43614 | 5/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29947133 | 0.83 | POLB (0.49) | LIPELIPGHCRTR1HCRTR2 | |
| SCHEMBL29947145 | 0.81 | PDE3B (0.41) | — | |
| SCHEMBL23708283 | 0.80 | LIPG (0.60) | LIPELIPGHCRTR1HCRTR2 | |
| SCHEMBL29995288 | 0.80 | LIPG (0.60) | LIPELIPGHCRTR1HCRTR2 | |
| SCHEMBL23702791 | 0.80 | LIPG (0.60) | LIPELIPGHCRTR1HCRTR2 | |
| SCHEMBL29995239 | 0.80 | LIPG (0.60) | LIPELIPGHCRTR1HCRTR2 | |
| SCHEMBL26620485 | 0.80 | LIPG (0.60) | LIPELIPGHCRTR1HCRTR2 | |
| SCHEMBL23702751 | 0.79 | LIPG (0.62) | LIPELIPGHCRTR1HCRTR2 | |
| SCHEMBL23703427 | 0.79 | LIPG (0.62) | LIPELIPGHCRTR1HCRTR2 | |
| SCHEMBL23708114 | 0.79 | LIPG (0.62) | LIPELIPGHCRTR1HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4337206-A1 | HETEROCYCLIC TRPML1 AGONISTS AND USES THEREOF | Libra Therapeutics, Inc. (US) | 2024-03-20 | — | — | EP | disclosed |
| WO-2022240992-A1 | HETEROCYCLIC TRPML1 AGONISTS AND USES THEREOF | LIBRA THERAPEUTICS, INC. (US) | 2022-11-17 | — | — | WO | disclosed |