Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FYN | P06241 | 3/20 | 0.33 |
| ▸ | TYK2 | P29597 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.30 |
| ▸ | FEN1 | P39748 | 1/20 | 0.30 |
| ▸ | BRD4 | O60885 | 1/20 | 0.30 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24776105 | 1.00 | FYN (0.33) | FYNTYK2MEN1POLBMAPT | |
| SCHEMBL24776196 | 0.84 | TYK2 (0.33) | FYNTYK2CHRM2CHRM3BRD4 | |
| SCHEMBL24823032 | 0.84 | FYN (0.32) | FYNTYK2MEN1MAPTKMT2A | |
| SCHEMBL24822793 | 0.83 | KDM4E (0.31) | FYNTYK2CHRM2CHRM3BRD4 | |
| SCHEMBL30079510 | 0.83 | KDM4E (0.31) | FYNTYK2CHRM2CHRM3BRD4 | |
| SCHEMBL30079478 | 0.81 | PTGS2 (0.36) | TYK2AOC3BRD4BRD3 | |
| SCHEMBL24823040 | 0.81 | PTGS2 (0.36) | TYK2AOC3BRD4BRD3 | |
| SCHEMBL24823464 | 0.80 | NLRP3 (0.33) | FYNALOX5APFEN1 | |
| SCHEMBL24822798 | 0.80 | TYK2 (0.31) | TYK2 | |
| SCHEMBL24822792 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4337648-A1 | SUBSTITUTED HETEROCYCLIC COMPOUNDS | Bristol-Myers Squibb Company (US) | 2024-03-20 | — | — | EP | disclosed |
| CN-117355514-A | Substituted heterocyclic compounds | 百时美施贵宝公司 | 2024-01-05 | — | — | CN | disclosed |
| WO-2022241174-A1 | SUBSTITUTED HETEROCYCLIC COMPOUNDS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2022-11-17 | — | — | WO | disclosed |