Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.33 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.33 |
| ▸ | AKT1 | P31749 | 1/20 | 0.33 |
| ▸ | BUB1 | O43683 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.32 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.31 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.30 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL715654 | 0.88 | BRD4 (0.39) | L3MBTL1PRMT5WDR77AKT1BUB1 | |
| SCHEMBL30606423 | 0.88 | BRD4 (0.39) | L3MBTL1PRMT5WDR77AKT1BUB1 | |
| SCHEMBL1720935 | 0.81 | P2RX4 (0.35) | NOTUM | |
| SCHEMBL2574877 | 0.76 | NOTUM (0.39) | NOTUM | |
| SCHEMBL21624141 | 0.76 | NOTUM (0.52) | CREBBPNOTUM | |
| SCHEMBL20798845 | 0.75 | BRD4 (0.38) | L3MBTL1AKT1BUB1BRD4CREBBP | |
| SCHEMBL23344114 | 0.75 | LMNA (0.43) | NOTUM | |
| SCHEMBL29698752 | 0.74 | L3MBTL1 (0.49) | L3MBTL1BUB1BRD4CREBBPACHE | |
| SCHEMBL1054068 | 0.74 | L3MBTL1 (0.49) | L3MBTL1BUB1BRD4CREBBPACHE | |
| SCHEMBL23344126 | 0.73 | PRMT5 (0.42) | PRMT5WDR77AAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115135659-A | Morpholine derivatives and preparation method and application thereof | 深圳微芯生物科技股份有限公司 | 2022-09-30 | — | — | CN | disclosed |