Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.52 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.47 |
| ▸ | WNT3A | P56704 | 1/20 | 0.47 |
| ▸ | GRM4 | Q14833 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.40 |
| ▸ | CYP46A1 | Q9Y6A2 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL249470 | 1.00 | P2RX7 (0.56) | P2RX7MAPK1CTNNB1WNT3AGRM4 | |
| Hydrochloric Acid SCHEMBL28392257 | 0.98 | P2RX7 (0.55) | P2RX7MAPK1CTNNB1WNT3AGRM4 | |
| Formic Acid SCHEMBL15822388 | 0.93 | P2RX7 (0.50) | P2RX7MAPK1CTNNB1WNT3AGRM4 | |
| SCHEMBL28281561 | 0.87 | P2RX7 (0.53) | P2RX7MAPK1CTNNB1WNT3AGRM4 | |
| SCHEMBL29112193 | 0.83 | KDM4E (0.50) | P2RX7MAPK1KDM4EALDH1A1POLB | |
| SCHEMBL30629294 | 0.82 | P2RX7 (0.44) | P2RX7MAPK1CTNNB1WNT3AGRM4 | |
| SCHEMBL11881388 | 0.81 | P2RX7 (0.49) | P2RX7MAPK1CTNNB1WNT3AGRM4 | |
| SCHEMBL1478698 | 0.80 | P2RX7 (0.52) | P2RX7CTNNB1WNT3AGRM4FAAH | |
| SCHEMBL28179627 | 0.80 | P2RX7 (0.56) | P2RX7CTNNB1WNT3AGRM4FAAH | |
| SCHEMBL23293557 | 0.79 | P2RX7 (0.47) | P2RX7MAPK1CTNNB1WNT3AGRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115135659-A | Morpholine derivatives and preparation method and application thereof | 深圳微芯生物科技股份有限公司 | 2022-09-30 | — | — | CN | disclosed |