SCHEMBL29947748

SCHEMBL29947748

C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H]1CCCN1)C(=O)O

nearest known ligand 0.59

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
CTSC P53634 3/20 0.59
REN P00797 1/20 0.52
PSMB5 P28074 4/20 0.49
CALCRL Q16602 1/20 0.48
LMNA P02545 1/20 0.48
TDP1 Q9NUW8 1/20 0.48
LTA4H P09960 2/20 0.47
MME P08473 1/20 0.47
GHSR Q92847 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29437874 0.91 CTSC (0.49) CTSCRENCALCRL
SCHEMBL29437875 0.90 NTSR2 (0.49) CTSCRENCALCRLMME
SCHEMBL29630530 0.90 CTSC (0.51) CTSCRENPSMB5CALCRLLTA4H
SCHEMBL30546877 0.90 CTSC (0.63) CTSCRENPSMB5LMNATDP1
SCHEMBL29701979 0.90 CTSC (0.63) CTSCRENPSMB5LMNATDP1
SCHEMBL29702042 0.90 CTSC (0.63) CTSCRENPSMB5LMNATDP1
SCHEMBL30053097 0.89 CTSC (0.57) CTSCRENPSMB5CALCRLLMNA
SCHEMBL29958630 0.88 REN (0.58) CTSCRENPSMB5MME
SCHEMBL29695560 0.88 CTSC (0.58) CTSCRENCALCRLLMNATDP1
SCHEMBL31026629 0.87 CTSC (0.68) CTSCLMNATDP1MME

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4713025-A2 DELIVERY OF DUAL PAYLOAD OF MMAF OR MMAE AND TLR7 AGONISTS The Research Foundation for The State University of New York (US) 2026-03-25 EP claimed
US-20240189440-A1 TLR7 AND TLR8 AGONISTS FOR THE TREATMENT OF CANCER AND/OR INFECTIOUS DISEASES THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) 2024-06-13 US claimed
EP-4301417-A1 TLR7 AND TLR8 AGONISTS FOR THE TREATMENT OF CANCER AND/OR INFECTIOUS DISEASES The Research Foundation for The State University of New York (US) 2024-01-10 EP claimed
WO-2022187809-A1 TLR7 AND TLR8 AGONISTS FOR THE TREATMENT OF CANCER AND/OR INFECTIOUS DISEASES THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) 2022-09-09 WO claimed
US-12622975-B2 Peptide-conjugated prodrugs BRANDEIS UNIVERSITY (US) 2026-05-12 US disclosed
EP-4713025-A2 DELIVERY OF DUAL PAYLOAD OF MMAF OR MMAE AND TLR7 AGONISTS The Research Foundation for The State University of New York (US) 2026-03-25 EP disclosed
CN-121574191-A Myristoyl pentapeptide-17 and preparation method and application thereof 深圳连续制药科技有限公司 2026-02-27 CN disclosed
US-20240189440-A1 TLR7 AND TLR8 AGONISTS FOR THE TREATMENT OF CANCER AND/OR INFECTIOUS DISEASES THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) 2024-06-13 US disclosed
EP-4301417-A1 TLR7 AND TLR8 AGONISTS FOR THE TREATMENT OF CANCER AND/OR INFECTIOUS DISEASES The Research Foundation for The State University of New York (US) 2024-01-10 EP disclosed
EP-4201951-B1 METHOD FOR PEPTIDE SYNTHESIS BACHEM HOLDING AG (CH) 2023-11-22 EP disclosed
WO-2023117904-A1 METHOD FOR PEPTIDE SYNTHESIS BACHEM HOLDING AG (CH) 2023-06-29 WO disclosed
EP-4201951-A1 METHOD FOR PEPTIDE SYNTHESIS Bachem Holding AG (CH) 2023-06-28 EP disclosed
US-20220387610-A1 PEPTIDE-CONJUGATED PRODRUGS NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2022-12-08 US disclosed
WO-2022187809-A1 TLR7 AND TLR8 AGONISTS FOR THE TREATMENT OF CANCER AND/OR INFECTIOUS DISEASES THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) 2022-09-09 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240189440-A1 TLR7 AND TLR8 AGONISTS FOR THE TREATMENT OF CANCER AND/OR INFECTIOUS DISEASES TLR7, TLR8, TLR9 CTSC 1982/4885REN 4405/4885PSMB5 3309/4885
US-12622975-B2 Peptide-conjugated prodrugs PEPD, PAM, VIP CTSC 131/4885REN 2773/4885PSMB5 3664/4885
US-20220387610-A1 PEPTIDE-CONJUGATED PRODRUGS VIP, DNPEP, PEPD CTSC 37/4885REN 3056/4885PSMB5 3085/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.