Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 8/20 | 0.47 |
| ▸ | DHFR | P00374 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | SRC | P12931 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | CDC25B | P30305 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12424686 | 0.82 | SIGMAR1 (0.49) | SIGMAR1DHFRMEN1KMT2AKDM1A | |
| SCHEMBL1414206 | 0.79 | SIGMAR1 (0.57) | SIGMAR1DHFRALDH1A1 | |
| SCHEMBL12048739 | 0.79 | SIGMAR1 (0.50) | SIGMAR1DHFRMCL1EGFRTSHR | |
| SCHEMBL29467773 | 0.78 | DHFR (0.42) | SIGMAR1DHFRMEN1KMT2AMCL1 | |
| SCHEMBL14465459 | 0.78 | SIGMAR1 (0.49) | SIGMAR1DHFRMCL1 | |
| SCHEMBL12048709 | 0.78 | SIGMAR1 (0.49) | SIGMAR1DHFRMCL1SLC6A2SLC6A4 | |
| SCHEMBL12258277 | 0.77 | DHFR (0.49) | SIGMAR1DHFRMCL1TSHRALDH1A1 | |
| SCHEMBL1683320 | 0.75 | SIGMAR1 (0.63) | SIGMAR1DHFRMCL1TSHRALDH1A1 | |
| SCHEMBL12048742 | 0.75 | DHFR (0.45) | SIGMAR1DHFRMEN1KMT2ACYP3A4 | |
| SCHEMBL12048744 | 0.74 | DHFR (0.47) | SIGMAR1DHFRKMT2AMCL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115260041-A | Novel anti-aging agent and preparation method thereof | 王兴路 | 2022-11-01 | — | — | CN | disclosed |