Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | BCAT1 | P54687 | 1/20 | 0.32 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.31 |
| ▸ | KDR | P35968 | 2/20 | 0.31 |
| ▸ | ELANE | P08246 | 1/20 | 0.30 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.30 |
| ▸ | ABL1 | P00519 | 1/20 | 0.30 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.30 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28877272 | 1.00 | KDM4E (0.40) | KDM4EATML3MBTL1ALDH1A1LMNA | |
| SCHEMBL29947786 | 0.84 | KDM4E (0.42) | KDM4EATML3MBTL1ALDH1A1MAPK1 | |
| SCHEMBL28877240 | 0.84 | KDM4E (0.42) | KDM4EATML3MBTL1ALDH1A1MAPK1 | |
| SCHEMBL21890534 | 0.81 | KDM4E (0.49) | KDM4EATML3MBTL1ALDH1A1LMNA | |
| SCHEMBL28877250 | 0.77 | MAT2A (0.37) | KDM4EATML3MBTL1ALDH1A1LMNA | |
| SCHEMBL29947909 | 0.77 | MAT2A (0.37) | KDM4EATML3MBTL1ALDH1A1LMNA | |
| SCHEMBL28957870 | 0.76 | CHEK1 (0.49) | MEN1KMT2AERBB2KDRCHEK1 | |
| SCHEMBL16122092 | 0.75 | KDM4E (0.47) | KDM4EATML3MBTL1ALDH1A1LMNA | |
| SCHEMBL21377910 | 0.72 | KDM4E (0.47) | KDM4EATML3MBTL1ALDH1A1LMNA | |
| SCHEMBL23542987 | 0.72 | ATM (0.44) | KDM4EATML3MBTL1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115260245-A | Iridium metal complex, application thereof and organic electroluminescent device | 清华大学 | 2022-11-01 | — | — | CN | disclosed |