Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | XBP1 | P17861 | 1/20 | 0.34 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.33 |
| ▸ | MAT2A | P31153 | 5/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.32 |
| ▸ | JAK2 | O60674 | 1/20 | 0.31 |
| ▸ | JAK3 | P52333 | 1/20 | 0.31 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.31 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29947786 | 1.00 | KDM4E (0.42) | KDM4EATML3MBTL1MAPK1HTT | |
| SCHEMBL29947873 | 0.84 | KDM4E (0.40) | KDM4EATML3MBTL1MAPK1ALDH1A1 | |
| SCHEMBL28877272 | 0.84 | KDM4E (0.40) | KDM4EATML3MBTL1MAPK1ALDH1A1 | |
| SCHEMBL21213713 | 0.83 | KDM4E (0.49) | KDM4EATML3MBTL1MAPK1HTT | |
| SCHEMBL28877250 | 0.78 | MAT2A (0.37) | KDM4EATML3MBTL1MAPK1ALDH1A1 | |
| SCHEMBL29947909 | 0.78 | MAT2A (0.37) | KDM4EATML3MBTL1MAPK1ALDH1A1 | |
| SCHEMBL28963945 | 0.78 | KDM4E (0.49) | KDM4EATML3MBTL1MAPK1HTT | |
| SCHEMBL30180813 | 0.78 | KDM4E (0.49) | KDM4EATML3MBTL1MAPK1HTT | |
| SCHEMBL20659815 | 0.78 | L3MBTL1 (0.43) | KDM4EATML3MBTL1MAPK1HTT | |
| SCHEMBL21679704 | 0.74 | KDM4E (0.50) | KDM4EATML3MBTL1MAPK1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115260245-A | Iridium metal complex, application thereof and organic electroluminescent device | 清华大学 | 2022-11-01 | — | — | CN | disclosed |