Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 4/20 | 0.38 |
| ▸ | CA2 | P00918 | 4/20 | 0.38 |
| ▸ | CA4 | P22748 | 4/20 | 0.38 |
| ▸ | CA9 | Q16790 | 4/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.31 |
| ▸ | PARP1 | P09874 | 1/20 | 0.31 |
| ▸ | SMYD3 | Q9H7B4 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL918097 | 0.86 | CA1 (0.36) | CA1CA2CA4CA9DPP4 | |
| SCHEMBL4678845 | 0.86 | CA1 (0.36) | CA1CA2CA4CA9DPP4 | |
| SCHEMBL1715152 | 0.86 | CA1 (0.36) | CA1CA2CA4CA9DPP4 | |
| Hydrochloric Acid SCHEMBL17560356 | 0.85 | CA1 (0.35) | CA1CA2CA4CA9DPP4 | |
| Hydrochloric Acid SCHEMBL38666765 | 0.85 | CA1 (0.35) | CA1CA2CA4CA9DPP4 | |
| Piperazine SCHEMBL2231464 | 0.83 | CA1 (0.34) | CA1CA2CA4CA9KMT2A | |
| SCHEMBL4983271 | 0.81 | CA1 (0.37) | CA1CA2CA4CA9ADRB1 | |
| SCHEMBL29947739 | 0.80 | PARP1 (0.50) | CA1CA2CA4CA9PARP1 | |
| SCHEMBL29527992 | 0.80 | PARP1 (0.50) | CA1CA2CA4CA9PARP1 | |
| Fumaric Acid SCHEMBL4680666 | 0.79 | CA1 (0.33) | CA1CA2CA4CA9DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4076667-A1 | TRICYCLIC PYRIDONES AND PYRIMIDONES | Erasca, Inc. (US) | 2022-10-26 | — | — | EP | disclosed |