Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 2/20 | 0.47 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.47 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.40 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.39 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.39 |
| ▸ | CDK2 | P24941 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.37 |
| ▸ | KIT | P10721 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.36 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | MAP2K4 | P45985 | 1/20 | 0.36 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.36 |
| ▸ | MAPKAPK3 | Q16644 | 1/20 | 0.36 |
| ▸ | MAPK6 | Q16659 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5065601 | 0.81 | PDE3B (0.47) | PDE3BPDE3AKDM4EALDH1A1NISCH | |
| SCHEMBL17151506 | 0.81 | PDE3B (0.47) | PDE3BPDE3APDGFRBPDPK1 | |
| SCHEMBL13619228 | 0.81 | NISCH (0.56) | KDM4EALDH1A1NISCHMEN1KMT2A | |
| SCHEMBL13619043 | 0.81 | PDE3B (0.47) | PDE3BPDE3AKDM4EALDH1A1PDGFRB | |
| SCHEMBL5065569 | 0.81 | MTOR (0.53) | PDE3BPDE3AKDM4EALDH1A1NISCH | |
| SCHEMBL15144399 | 0.77 | PDE3B (0.51) | PDE3BPDE3AKDM4EALDH1A1PDGFRB | |
| SCHEMBL6619540 | 0.73 | DAO (0.42) | PDE3BPDE3AKDM4EALDH1A1DAO | |
| SCHEMBL183153 | 0.72 | NISCH (0.64) | PDE3BPDE3ARIPK1CDK2KDM4E | |
| SCHEMBL30719409 | 0.72 | AURKA (0.40) | ALDH1A1MAPK1NISCH | |
| SCHEMBL3949651 | 0.70 | KDM5B (0.42) | PDE3BPDE3AKDM4EALDH1A1KIT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112858519-B | Detection method for related substances of amoxicillin potassium clavulanate granules | 黑龙江全乐制药有限公司 | 2022-12-02 | — | — | CN | claimed |
| CN-118731216-A | Detection method of related substances of amoxicillin and clavulanate potassium tablets | 广州白云山医药集团股份有限公司白云山制药总厂 | 2024-10-01 | — | — | CN | disclosed |
| CN-112305117-B | Chromatographic detection method for determining related substances of amoxicillin and clavulanate potassium | 四川制药制剂有限公司 | 2022-09-09 | — | — | CN | disclosed |