Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKA | O14965 | 1/20 | 0.40 |
| ▸ | TTK | P33981 | 1/20 | 0.40 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.40 |
| ▸ | INCENP | Q9NQS7 | 1/20 | 0.40 |
| ▸ | KDM5B | Q9UGL1 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.32 |
| ▸ | GSK3B | P49841 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | MTOR | P42345 | 1/20 | 0.31 |
| ▸ | ADK | P55263 | 1/20 | 0.31 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | PIM1 | P11309 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.30 |
| ▸ | KDM4A | O75164 | 1/20 | 0.30 |
| ▸ | KDM4B | O94953 | 1/20 | 0.30 |
| ▸ | KDM5C | P41229 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5065569 | 0.74 | MTOR (0.53) | MAPTALDH1A1MTORADKNISCH | |
| SCHEMBL30719412 | 0.74 | ACVR1 (0.41) | AURKAAURKBINCENPKDM5BALDH1A1 | |
| SCHEMBL29096364 | 0.72 | P2RX7 (0.37) | KDM5BNISCHPIM1KDM4AKDM4B | |
| SCHEMBL29948010 | 0.72 | PDE3B (0.47) | ALDH1A1NISCHMAPK1 | |
| SCHEMBL13619043 | 0.72 | PDE3B (0.47) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL17151506 | 0.72 | PDE3B (0.47) | — | |
| SCHEMBL5065601 | 0.72 | PDE3B (0.47) | AURKAAURKBINCENPKDM5BMAPT | |
| SCHEMBL13619228 | 0.72 | NISCH (0.56) | AURKBINCENPMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL1578108 | 0.71 | NISCH (0.54) | CYP2A6ALDH1A1SMN1; SMN2MTORADK | |
| SCHEMBL14859149 | 0.70 | AURKA (0.47) | AURKATTKAURKBINCENPKDM5B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112513020-B | KDM1A inhibitors for the treatment of diseases | 伊美格生物科学公司 | 2024-02-23 | — | — | CN | disclosed |