SCHEMBL183153

SCHEMBL183153

Oc1ccc(-c2ncc[nH]2)cc1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NISCH Q9Y2I1 2/20 0.64
MTOR P42345 1/20 0.63
ADK P55263 1/20 0.63
ALDH1A1 P00352 4/20 0.61
KDM4E B2RXH2 2/20 0.61
CYP1A2 P05177 1/20 0.51
CYP3A4 P08684 1/20 0.51
CYP2D6 P10635 1/20 0.51
CYP19A1 P11511 1/20 0.51
CYP2C9 P11712 1/20 0.51
CYP2C19 P33261 1/20 0.51
PDE3B Q13370 1/20 0.50
PDE3A Q14432 1/20 0.50
SMPD3 Q9NY59 1/20 0.49
PDE4A P27815 2/20 0.45
PDE4B Q07343 2/20 0.45
PDE4C Q08493 2/20 0.45
PDE4D Q08499 2/20 0.45
PARP1 P09874 1/20 0.43
GAA P10253 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL722191 0.89 NISCH (0.78) NISCHMTORADKALDH1A1KDM4E
SCHEMBL862114 0.86 NISCH (0.75) NISCHMTORADKALDH1A1KDM4E
SCHEMBL9730414 0.84 NISCH (0.47) NISCHMTORADKALDH1A1KDM4E
SCHEMBL6055553 0.83 NISCH (0.47) NISCHMTORADKALDH1A1KDM4E
SCHEMBL6055813 0.83 NISCH (0.47) NISCHMTORADKALDH1A1KDM4E
SCHEMBL29140136 0.81 ALDH1A1 (0.70) NISCHMTORADKALDH1A1KDM4E
SCHEMBL28823231 0.80 NISCH (0.67) NISCHMTORADKALDH1A1KDM4E
SCHEMBL8540913 0.80 ESR1 (0.49) NISCHMTORADKALDH1A1KDM4E
SCHEMBL31331594 0.79 NISCH (0.41) NISCHMTORADKALDH1A1KDM4E
SCHEMBL674010 0.78 NISCH (1.00) NISCHMTORADKALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 336 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4273130-B1 PROCESS FOR SYNTHESIZING ZWITTERIONIC BASES, ZWITTERIONIC BASES, PROCESS FOR CAPTURING CO2 AND USE PETROLEO BRASILEIRO SA PETROBRAS (BR) 2025-12-03 EP claimed
CN-119409751-A Ammonia decomposition reagent and application thereof in diaminopurine oligonucleotide synthesis 中肽生化有限公司 2025-02-11 CN claimed
US-20240131467-A1 PROCESS FOR SYNTHESIZING ZWITTERIONIC BASES, ZWITTERIONIC BASES, PROCESS FOR CAPTURING CO2 AND USE PETROLEO BRASILEIRO S A – PETROBRAS (BR) 2024-04-25 US claimed
CN-117157134-A Method for synthesizing zwitterionic base, method for capturing CO2 and use 巴西石油公司 2023-12-01 CN claimed
EP-4273130-A1 PROCESS FOR SYNTHESIZING ZWITTERIONIC BASES, ZWITTERIONIC BASES, PROCESS FOR CAPTURING CO2 AND USE Petróleo Brasileiro S.A. - Petrobras (BR) 2023-11-08 EP claimed
US-RE49466-E1 Solution phase homogeneous assays BECKMAN COULTER, INC. (US) 2023-03-21 US claimed
CN-113816372-B Heteroatom-doped nitrogen-containing heterocyclic ligand derived carbon material and application thereof 温州大学 2023-03-21 CN claimed
WO-2022140827-A1 PROCESS FOR SYNTHESIZING ZWITTERIONIC BASES, ZWITTERIONIC BASES, PROCESS FOR CAPTURING CO2 AND USE Petróleo Brasileiro S.A. - Petrobras (BR) 2022-07-07 WO claimed
CN-113816372-A Heteroatom-doped nitrogen-containing heterocyclic ligand derived carbon material and application thereof 温州大学 2021-12-21 CN claimed
CN-112986221-A Method for detecting substance to be detected in sample and kit thereof 利多(香港)有限公司 2021-06-18 CN claimed
EP-0958287-A1 SULFAMIDE-METALLOPROTEASE INHIBITORS F. HOFFMANN-LA ROCHE AG (CH) 1999-11-24 EP claimed
EP-0938677-A1 CHEMILUMINESCENT DETECTION METHODS USING DUAL ENZYME-LABELED BINDING PARTNERS LUMIGEN, INC. (US) 1999-09-01 EP claimed
US-5922558-A REACTING A PEROXIDASE ENZYME WITH A PEROXIDE AND AT LEAST ONE NOVEL COMPOUND HAVING AN ELECTRON RICH C-C DOUBLE BOND REACTIVE TO PEROXIDASE AND THE PEROXIDE TO PRODUCE AN EXCITED STATE COMPOUND; ALSO USEFUL IN ASSAYS FOR PEROXIDASE ENZYMES LUMIGEN, INC. (US) 1999-07-13 US claimed
WO-1999014358-A1 CHEMILUMINESCENCE COMPOSITIONS AND METHODS LUMIGEN, INC. (US) 1999-03-25 WO claimed
US-5843666-A Chemiluminescent detection methods using dual enzyer-labeled binding partners LUMIGEN, INC. (US) 1998-12-01 US claimed
WO-1998032748-A1 SULFAMIDE-METALLOPROTEASE INHIBITORS F. HOFFMANN-LA ROCHE AG (CH) 1998-07-30 WO claimed
WO-1998021586-A1 CHEMILUMINESCENT DETECTION METHODS USING DUAL ENZYME-LABELED BINDING PARTNERS LUMIGEN, INC. (US) 1998-05-22 WO claimed
CN-1034174-C Certain imidazoquinoxalines, a new class of GABA brain receptor ligands NEUROGEN CORP (US) 1997-03-05 CN claimed
EP-0692033-A1 ENHANCEMENT OF CHEMILUMINESCENT REACTIONS BTG INTERNATIONAL LIMITED (GB) 1996-01-17 EP claimed
CN-1076930-A Some imidazo quinoxaline compound; The γ-An Jidingsuan brain receptor ligands that one class is new NEUROGEN CORP (US) 1993-10-06 CN claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240131467-A1 PROCESS FOR SYNTHESIZING ZWITTERIONIC BASES, ZWITTERIONIC BASES, PROCESS FOR CAPTURING CO2 AND USE ZW10, CA2, CA4 NISCH 566/4885MTOR 3700/4885ADK 1169/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.