Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NUDT1 | P36639 | 1/20 | 0.40 |
| ▸ | METAP1 | P53582 | 2/20 | 0.36 |
| ▸ | METAP2 | P50579 | 1/20 | 0.36 |
| ▸ | AURKA | O14965 | 5/20 | 0.33 |
| ▸ | PDE5A | O76074 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | KIF11 | P52732 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.32 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.32 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL40861 | 0.94 | — | — | |
| SCHEMBL29376620 | 0.94 | — | — | |
| SCHEMBL28611928 | 0.92 | NUDT1 (0.42) | NUDT1METAP1METAP2AURKAPDE5A | |
| SCHEMBL27759739 | 0.92 | NUDT1 (0.42) | NUDT1METAP1METAP2AURKAPDE5A | |
| SCHEMBL21990259 | 0.92 | NUDT1 (0.42) | NUDT1METAP1METAP2AURKAPDE5A | |
| SCHEMBL8038689 | 0.92 | NUDT1 (0.42) | NUDT1METAP1METAP2AURKAPDE5A | |
| Iodide SCHEMBL16585403 | 0.92 | NUDT1 (0.42) | NUDT1METAP1METAP2AURKAPDE5A | |
| Hydrochloric Acid SCHEMBL29236109 | 0.92 | NUDT1 (0.42) | NUDT1METAP1METAP2AURKAPDE5A | |
| Pyrazine SCHEMBL27939229 | 0.88 | NUDT1 (0.40) | NUDT1METAP1METAP2AURKAPDE5A | |
| SCHEMBL937094 | 0.86 | NUDT1 (0.39) | NUDT1METAP1METAP2AURKAPDE5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240059725-A1 | COUMARIN COMPOUNDS AND A PROCESS FOR PREPARATION THEREOF | Majumder, Suman (IN) | 2024-02-22 | — | — | US | claimed |
| WO-2022238741-A1 | COUMARIN COMPOUNDS AND A PROCESS FOR PREPARATION THEREOF | MAJUMDER SUMAN (IN) | 2022-11-17 | — | — | WO | claimed |
| US-20240059725-A1 | COUMARIN COMPOUNDS AND A PROCESS FOR PREPARATION THEREOF | Majumder, Suman (IN) | 2024-02-22 | — | — | US | disclosed |
| WO-2022238741-A1 | COUMARIN COMPOUNDS AND A PROCESS FOR PREPARATION THEREOF | MAJUMDER SUMAN (IN) | 2022-11-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240059725-A1 | COUMARIN COMPOUNDS AND A PROCESS FOR PREPARATION THEREOF | NQO1, VKORC1, VKORC1L1 | NUDT1 662/4885METAP1 2239/4885METAP2 4032/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.