Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKN1 | Q16512 | 1/20 | 0.38 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.38 |
| ▸ | PTGER4 | P35408 | 8/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
| ▸ | JAK2 | O60674 | 1/20 | 0.34 |
| ▸ | JAK1 | P23458 | 1/20 | 0.34 |
| ▸ | TYK2 | P29597 | 1/20 | 0.34 |
| ▸ | JAK3 | P52333 | 1/20 | 0.34 |
| ▸ | F11 | P03951 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | SYK | P43405 | 1/20 | 0.33 |
| ▸ | IDH1 | O75874 | 1/20 | 0.33 |
| ▸ | CD38 | P28907 | 1/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23529317 | 1.00 | PKN1 (0.38) | PKN1PKN2PTGER4HPGDPARP1 | |
| SCHEMBL23529310 | 0.87 | PKN1 (0.43) | PKN1PKN2PTGER4PARP1JAK2 | |
| SCHEMBL29948273 | 0.87 | PKN1 (0.43) | PKN1PKN2PTGER4PARP1JAK2 | |
| SCHEMBL29948164 | 0.86 | PTGER4 (0.41) | PKN1PKN2PTGER4GRM2 | |
| SCHEMBL23529383 | 0.86 | PKN1 (0.37) | PKN1PKN2PTGER4PARP1SYK | |
| SCHEMBL29948198 | 0.86 | PKN1 (0.37) | PKN1PKN2PTGER4PARP1SYK | |
| SCHEMBL23552398 | 0.86 | PTGER4 (0.41) | PKN1PKN2PTGER4GRM2 | |
| SCHEMBL23529396 | 0.79 | GPR35 (0.35) | PKN1PKN2PARP1 | |
| SCHEMBL29948116 | 0.79 | GPR35 (0.35) | PKN1PKN2PARP1 | |
| SCHEMBL23529303 | 0.79 | PTGER4 (0.41) | PKN1PKN2PTGER4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114981265-B | Compounds of formula (I) | CTXT私人有限公司 | 2025-01-03 | — | — | CN | disclosed |
| WO-2022266711-A1 | SUBSTITUTED AMIDOBENZIMIDAZOLE DIMERS AS STING MODULATORS | Aculeus Therapeutics Pty Ltd (AU) | 2022-12-29 | — | — | WO | disclosed |
| EP-4077318-A1 | COMPOUNDS | CTXT PTY LTD (AU) | 2022-10-26 | — | — | EP | disclosed |