Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | DHODH | Q02127 | 3/20 | 0.49 |
| ▸ | CDC7 | O00311 | 9/20 | 0.47 |
| ▸ | DBF4 | Q9UBU7 | 9/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | TRPM8 | Q7Z2W7 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.45 |
| ▸ | CRHBP | P24387 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL300086 | 0.89 | KDM4E (0.49) | ALDH1A1HPGDCDC7DBF4KDM4E | |
| SCHEMBL289847 | 0.85 | KDM4E (0.64) | ALDH1A1HPGDDHODHCDC7DBF4 | |
| SCHEMBL13064837 | 0.77 | ALDH1A1 (0.46) | ALDH1A1HPGDDHODHCDC7DBF4 | |
| SCHEMBL4471162 | 0.76 | MAPT (0.76) | ALDH1A1HPGDDHODHCDC7DBF4 | |
| SCHEMBL298659 | 0.74 | CDC7 (0.61) | ALDH1A1HPGDCDC7DBF4MAPT | |
| SCHEMBL10242354 | 0.74 | ALDH1A1 (0.72) | ALDH1A1HPGDDHODHCDC7DBF4 | |
| SCHEMBL24303679 | 0.73 | MAPT (0.62) | DHODHCDC7DBF4KDM4ETRPM8 | |
| SCHEMBL3827647 | 0.72 | KDM4E (0.69) | ALDH1A1HPGDDHODHCDC7DBF4 | |
| SCHEMBL10820916 | 0.72 | ALDH1A1 (0.68) | ALDH1A1HPGDDHODHCDC7DBF4 | |
| SCHEMBL289519 | 0.72 | ALDH1A1 (1.00) | ALDH1A1HPGDDHODHCDC7DBF4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2427447-A2 | SMALL MOLECULE INHIBITORS OF INFLUENZA A AND B VIRUS AND RESPIRATORY SYNCYTIAL VIRUS REPLICATION | Pike Pharma GmbH (CH) | 2012-03-14 | — | — | EP | disclosed |
| WO-2010128163-A2 | SMALL MOLECULE INHIBITORS OF INFLUENZA A AND B VIRUS AND RESPIRATORY SYNCYTIAL VIRUS REPLICATION | PIKE PHARMA GMBH (CH) | 2010-11-11 | — | — | WO | disclosed |