Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.38 |
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | BLM | P54132 | 4/20 | 0.38 |
| ▸ | RECQL | P46063 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.38 |
| ▸ | APEX1 | P27695 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | BRCA1 | P38398 | 2/20 | 0.38 |
| ▸ | SLC10A1 | Q14973 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 5/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL168580 | 1.00 | HTT (0.40) | HTTKDM4EALDH1A1KMT2AMAPT | |
| SCHEMBL381650 | 0.98 | HTT (0.39) | HTTKDM4EALDH1A1KMT2AMAPT | |
| SCHEMBL381648 | 0.98 | HTT (0.39) | HTTKDM4EALDH1A1KMT2AMAPT | |
| SCHEMBL15522479 | 0.95 | HTT (0.39) | HTTKDM4EALDH1A1KMT2AMAPT | |
| SCHEMBL592737 | 0.95 | HTT (0.39) | HTTKDM4EALDH1A1KMT2AMAPT | |
| SCHEMBL19939980 | 0.93 | HTT (0.35) | HTTKDM4EALDH1A1KMT2AMAPT | |
| SCHEMBL9614018 | 0.93 | MAPT (0.37) | HTTKDM4EALDH1A1KMT2AMAPT | |
| SCHEMBL9614427 | 0.90 | MAPT (0.37) | HTTKDM4EALDH1A1KMT2AMAPT | |
| SCHEMBL17733109 | 0.89 | KMT2A (0.43) | HTTKDM4EALDH1A1KMT2AMAPT | |
| SCHEMBL218851 | 0.86 | HTT (0.39) | HTTKDM4EALDH1A1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4077707-A1 | A REAL-TIME, ADD-AND-READ FLUORESCENCE-BASED ASSAY FOR TESTING FUNCTION AND DRUG INTERACTIONS OF OATP TRANSPORTERS | Cellpharma Kft. (HU) | 2022-10-26 | — | — | EP | claimed |
| EP-3606639-B1 | METHOD AND SYSTEM FOR SEPARATING BIOMOLECULES FROM A MIXTURE CONTAINING SAME | UNIV RAMOT (IL) | 2024-12-25 | — | — | EP | disclosed |
| EP-4077707-A1 | A REAL-TIME, ADD-AND-READ FLUORESCENCE-BASED ASSAY FOR TESTING FUNCTION AND DRUG INTERACTIONS OF OATP TRANSPORTERS | Cellpharma Kft. (HU) | 2022-10-26 | — | — | EP | disclosed |