Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | RECQL | P46063 | 3/20 | 0.38 |
| ▸ | BLM | P54132 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | APEX1 | P27695 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | BRCA1 | P38398 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29948312 | 0.98 | HTT (0.40) | HTTKMT2AKDM4EMAPTALDH1A1 | |
| SCHEMBL168580 | 0.98 | HTT (0.40) | HTTKMT2AKDM4EMAPTALDH1A1 | |
| SCHEMBL381648 | 0.97 | HTT (0.39) | HTTKMT2AKDM4EMAPTALDH1A1 | |
| SCHEMBL15522479 | 0.94 | HTT (0.39) | HTTKMT2AKDM4EMAPTALDH1A1 | |
| SCHEMBL592737 | 0.94 | HTT (0.39) | HTTKMT2AKDM4EMAPTALDH1A1 | |
| SCHEMBL19939980 | 0.91 | HTT (0.35) | HTTKMT2AKDM4EMAPTALDH1A1 | |
| SCHEMBL9614018 | 0.91 | MAPT (0.37) | HTTKMT2AKDM4EMAPTALDH1A1 | |
| SCHEMBL9614427 | 0.88 | MAPT (0.37) | HTTKMT2AKDM4EMAPTALDH1A1 | |
| SCHEMBL17733109 | 0.87 | KMT2A (0.43) | HTTKMT2AKDM4EMAPTALDH1A1 | |
| SCHEMBL218851 | 0.84 | HTT (0.39) | HTTKMT2AKDM4EMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11150358-B2 | Radiation dosimetry sol or gel and radiation dosimeter comprising same as material for radiation dosimetry | RIKEN (JP) | 2021-10-19 | — | — | US | disclosed |
| US-20210196842-A1 | SITE-SPECIFIC RADIOFLUORINATION OF PEPTIDES WITH 8-[18F]-FLUOROOCTANOIC ACID CATALYZED BY LIPOIC ACID LIGASE | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2021-07-01 | — | — | US | disclosed |
| US-20200333474-A1 | RADIATION DOSIMETRY SOL OR GEL AND RADIATION DOSIMETER COMPRISING SAME AS MATERIAL FOR RADIATION DOSIMETRY | RIKEN (JP) | 2020-10-22 | — | — | US | disclosed |
| EP-3686632-A1 | RADIATION DOSIMETRY SOL OR GEL AND RADIATION DOSIMETER COMPRISING SAME AS MATERIAL FOR RADIATION DOSIMETRY | Riken (JP) | 2020-07-29 | — | — | EP | disclosed |
| US-9850383-B2 | Uncharged pyrenyloxy sulfonamide dyes for conjugation with biomolecules | GENE TOOLS, LLC (US) | 2017-12-26 | — | — | US | disclosed |
| US-20170210904-A1 | Uncharged pyrenyloxy sulfonamide dyes for conjugation with biomolecules | GENE TOOLS, LLC | 2017-07-27 | — | — | US | disclosed |
| WO-2017095806-A1 | SITE-SPECIFIC RADIOFLUORINATION OF PEPTIDES WITH 8-[18F]-FLUOROOCTANOIC ACID CATALYZED BY LIPOIC ACID LIGASE | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2017-06-08 | — | — | WO | disclosed |
| US-20170023681-A1 | PERSONAL AND SELF INDICATING RADIATION ALERT DOSIMETER | NEW YORK UNIVERSITY | 2017-01-26 | — | — | US | disclosed |
| US-9284541-B2 | Methods and compositions for protein labeling using lipoic acid ligases | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2016-03-15 | — | — | US | disclosed |
| US-9086489-B2 | Personal and area self-indicating instant radiation alert dosimeter | JP LABORATORIES, INC (US) | 2015-07-21 | — | — | US | disclosed |
| US-7227158-B1 | Stick-on self-indicating instant radiation dosimeter | JP LABS, INC. (US) | 2007-06-05 | — | — | US | disclosed |
| WO-2007041689-A2 | METHODS OF SITE-SPECIFIC LABELING OF MOLECULES AND MOLECULES PRODUCED THEREBY | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2007-04-12 | — | — | WO | disclosed |
| US-7172877-B2 | Methods and compositions for peptide and protein labeling | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2007-02-06 | — | — | US | disclosed |
| US-20060145091-A1 | Self indicating radiation alert dosimeter | JP LABORATORIES INC. | 2006-07-06 | — | — | US | disclosed |
| EP-1599744-A2 | SELF-INDICATING RADIATION ALERT DOSIMETER | JP LABORATORIES, INC. (US) | 2005-11-30 | — | — | EP | disclosed |
| US-20050233389-A1 | Methods and compositions for peptide and protein labeling | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2005-10-20 | — | — | US | disclosed |
| US-20040209317-A1 | Methods and compositions for peptide and protein labeling | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2004-10-21 | — | — | US | disclosed |
| WO-2004077097-A2 | SELF-INDICATING RADIATION ALERT DOSIMETER | JP LABORATORIES INC. (US) | 2004-09-10 | — | — | WO | disclosed |
| US-6487326-B1 | Thin film fiber optic electrode sensor array and apparatus | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM | 2002-11-26 | — | — | US | disclosed |
| WO-2001038853-A2 | THIN FILM FIBER OPTIC ELECTRODE SENSOR ARRAY AND APPARATUS | BOARD OF REGENTS THE UNIVERSITY OF TEXAS SYSTEM (US) | 2001-05-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050233389-A1 | Methods and compositions for peptide and protein labeling | HLCS, BTD, QPCTL | HTT 1661/4885KMT2A 3151/4885KDM4E 3349/4885 |
| US-20210196842-A1 | SITE-SPECIFIC RADIOFLUORINATION OF PEPTIDES WITH 8-[18F]-FLUOROOCTANOIC ACID CATALYZED BY LIPOIC ACID LIGASE | DLAT, FABP7, ACSL1 | HTT 2816/4885KMT2A 914/4885KDM4E 2077/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.