Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 9/20 | 0.70 |
| ▸ | CA1 | P00915 | 8/20 | 0.70 |
| ▸ | CA9 | Q16790 | 8/20 | 0.70 |
| ▸ | CA12 | O43570 | 5/20 | 0.70 |
| ▸ | CA4 | P22748 | 4/20 | 0.70 |
| ▸ | CA6 | P23280 | 4/20 | 0.70 |
| ▸ | CA5A | P35218 | 4/20 | 0.70 |
| ▸ | CA7 | P43166 | 4/20 | 0.70 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.70 |
| ▸ | CA5B | Q9Y2D0 | 4/20 | 0.70 |
| ▸ | G6PD | P11413 | 1/20 | 0.58 |
| ▸ | IDE | P14735 | 1/20 | 0.58 |
| ▸ | CA3 | P07451 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10694524 | 1.00 | CA2 (0.70) | CA2CA1CA9CA12CA4 | |
| SCHEMBL1006804 | 0.83 | G6PD (0.53) | CA2CA1CA9CA12CA4 | |
| SCHEMBL878968 | 0.83 | CA2 (1.00) | CA2CA1CA9CA12CA4 | |
| SCHEMBL2811342 | 0.83 | CA2 (0.76) | CA2CA1CA9CA12CA4 | |
| SCHEMBL30351262 | 0.83 | CA2 (1.00) | CA2CA1CA9CA12CA4 | |
| SCHEMBL4639254 | 0.81 | G6PD (0.60) | CA2CA1CA9CA12CA4 | |
| SCHEMBL898422 | 0.80 | G6PD (0.64) | CA2CA1CA9CA12CA4 | |
| SCHEMBL10688819 | 0.80 | CA2 (0.66) | CA2CA1CA9CA12CA4 | |
| SCHEMBL3434572 | 0.79 | CA2 (0.70) | CA2CA1CA9CA12CA4 | |
| SCHEMBL7769757 | 0.79 | CA2 (0.70) | CA2CA1CA9CA12CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4134364-B1 | BROMODOMAIN INHIBITORS | CELGENE QUANTICEL RES INC (US) | 2025-07-30 | — | — | EP | disclosed |
| EP-4384510-A1 | COMPOUNDS TARGETING MUTANT OF P53 | Jacobio Pharmaceuticals Co., Ltd. (CN) | 2024-06-19 | — | — | EP | disclosed |
| CN-117813295-A | Compounds targeting p53 mutants | 北京加科思新药研发有限公司 | 2024-04-02 | — | — | CN | disclosed |
| WO-2023016434-A1 | COMPOUNDS TARGETING MUTANT OF P53 | JACOBIO PHARMACEUTICALS CO., LTD. (CN) | 2023-02-16 | — | — | WO | disclosed |
| EP-4134364-A2 | BROMODOMAIN INHIBITORS | Celgene Quanticel Research, Inc. (US) | 2023-02-15 | — | — | EP | disclosed |
| EP-3640241-B1 | BROMODOMAIN INHIBITORS | CELGENE QUANTICEL RES INC (US) | 2022-09-28 | — | — | EP | disclosed |