Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | GBA2 | Q9HCG7 | 1/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
| ▸ | HRH2 | P25021 | 2/20 | 0.33 |
| ▸ | HRH1 | P35367 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.33 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.33 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29622490 | 0.83 | SMN1; SMN2 (0.40) | LMNASMN1; SMN2POLBALDH1A1ATM | |
| Oxalic Acid SCHEMBL31276257 | 0.83 | LMNA (0.41) | LMNASMN1; SMN2POLBALDH1A1ATM | |
| SCHEMBL29937233 | 0.78 | SMN1; SMN2 (0.42) | LMNASMN1; SMN2POLBALDH1A1ATM | |
| SCHEMBL21409258 | 0.77 | LMNA (0.54) | LMNASMN1; SMN2POLBALDH1A1OPRD1 | |
| Oxalic Acid SCHEMBL27086649 | 0.75 | SMN1; SMN2 (0.40) | LMNASMN1; SMN2POLBALDH1A1ATM | |
| SCHEMBL29751587 | 0.75 | LMNA (0.48) | LMNASMN1; SMN2POLBALDH1A1ATM | |
| SCHEMBL17017 | 0.74 | POLB (0.63) | LMNASMN1; SMN2POLBALDH1A1ATM | |
| SCHEMBL18760256 | 0.74 | POLB (0.63) | LMNASMN1; SMN2POLBALDH1A1ATM | |
| SCHEMBL5820669 | 0.74 | POLB (0.63) | LMNASMN1; SMN2POLBALDH1A1ATM | |
| SCHEMBL20570038 | 0.74 | LMNA (0.48) | LMNASMN1; SMN2POLBALDH1A1OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4076423-A1 | TRPML MODULATORS | Casma Therapeutics, Inc. (US) | 2022-10-26 | — | — | EP | disclosed |