Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.63 |
| ▸ | LMNA | P02545 | 1/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | HRH2 | P25021 | 3/20 | 0.43 |
| ▸ | HRH1 | P35367 | 3/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | GNAI3 | P08754 | 4/20 | 0.41 |
| ▸ | GNAO1 | P09471 | 4/20 | 0.41 |
| ▸ | GNAI1 | P63096 | 4/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | GBA2 | Q9HCG7 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5820669 | 1.00 | POLB (0.63) | POLBSMN1; SMN2LMNAALDH1A1HRH2 | |
| SCHEMBL18760256 | 1.00 | POLB (0.63) | POLBSMN1; SMN2LMNAALDH1A1HRH2 | |
| Hydrochloric Acid SCHEMBL1111003 | 0.98 | POLB (0.61) | POLBSMN1; SMN2LMNAALDH1A1HRH2 | |
| Potassium SCHEMBL30906131 | 0.98 | POLB (0.61) | POLBSMN1; SMN2LMNAALDH1A1HRH2 | |
| SCHEMBL4082478 | 0.98 | POLB (0.61) | POLBSMN1; SMN2LMNAALDH1A1HRH2 | |
| SCHEMBL5667296 | 0.95 | LMNA (0.57) | POLBSMN1; SMN2LMNAHRH2HRH1 | |
| SCHEMBL112600 | 0.94 | SMN1; SMN2 (0.56) | POLBSMN1; SMN2LMNAALDH1A1HRH2 | |
| SCHEMBL25424462 | 0.93 | LMNA (0.55) | POLBSMN1; SMN2LMNAGNAI3GNAO1 | |
| SCHEMBL27694189 | 0.93 | LMNA (0.55) | POLBSMN1; SMN2LMNAGNAI3GNAO1 | |
| SCHEMBL9123475 | 0.93 | LMNA (0.55) | POLBSMN1; SMN2LMNAGNAI3GNAO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 542 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116606292-A | Pyrido [1,2-a ] pyrimidinone derivatives containing sulfonamide unit, preparation method and application thereof | 贵州大学 | 2023-08-18 | — | — | CN | claimed |
| CN-109715639-A | Crystal form | 爱杜西亚药品有限公司 | 2019-05-03 | — | — | CN | claimed |
| CN-108586466-A | A kind of benzene phenodiazine * class HDM2 inhibitor and its preparation method and application | 中国药科大学 | 2018-09-28 | — | — | CN | claimed |
| CN-104529942-B | A kind of synthetic method of Vanoxerine | 天津孚音生物科技发展有限公司 | 2018-05-15 | — | — | CN | claimed |
| CN-104529942-A | Synthetic method for vanoxerine | TIANJIN FUYIN PHARMACEUTICAL INNOVATION CO LTD | 2015-04-22 | — | — | CN | claimed |
| EP-1989185-A1 | THERAPEUTIC COMPOUNDS | Helicon Therapeutics, Inc. (US) | 2008-11-12 | — | — | EP | claimed |
| WO-2007100851-A1 | THERAPEUTIC COMPOUNDS | HELICON THERAPEUTICS, INC. (US) | 2007-09-07 | — | — | WO | claimed |
| WO-2006137658-A1 | NEW SUBSTITUTED 1,3-THIAZOLE DERIVATIVES OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF HAVING IMMUNOSUPPRESSION AND INFLAMMATION INHIBITORY ACITIVITY, INTERMEDIATE COMPOUNDS OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF, A PROCESS FOR THE PREPARATION THEREOF, AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | DONGBU HITEK CO., LTD. (KR) | 2006-12-28 | — | — | WO | claimed |
| CN-1165539-C | Oxazinocarbazoles for the treatment of CNS diseases | �������Ŷ���Լ��������˾ | 2004-09-08 | — | — | CN | claimed |
| CN-1361781-A | Oxazinocarbazoles for the treatment of CNS diseases | UPJOHN CO (US) | 2002-07-31 | — | — | CN | claimed |
| EP-4747245-A1 | PHARMACEUTICAL COMPOUNDS | Almac Discovery Limited (GB) | 2026-05-27 | — | — | EP | disclosed |
| EP-4743446-A1 | NITRO-CONTAINING COMPOUNDS THAT KILL MYCOBACTERIA | Board of Trustees of Michigan State University (US) | 2026-05-20 | — | — | EP | disclosed |
| US-20260078219-A1 | Polymer Nanoaggregate Pharmaceutical Composition and Use Thereof | ANP TECHNOLOGIES, INC. (US) | 2026-03-19 | — | — | US | disclosed |
| US-12544342-B2 | Pharmaceutical composition containing taxane nanoaggregates and use thereof | FULGENT GENETICS, INC. (US) | 2026-02-10 | — | — | US | disclosed |
| WO-2025236100-A1 | SUBSTITUTED HETEROCYCLIC COMPOUNDS, COMPOSITIONS COMPRISING THEM AND USES THEREOF | Université de Montréal (CA) | 2025-11-20 | — | — | WO | disclosed |
| CN-1062904-A | ANTIPROLIFERATIVE SUBSTITUTED NAPHTHALENE COMPOUNDS | AGOURON PHARMA (US) | 1992-07-22 | — | — | CN | disclosed |
| EP-0276057-A2 | Piperazinylpyrimidines as beta-adrenergic receptor blocking agents | MERCK & CO. INC. (US) | 1988-07-27 | — | — | EP | disclosed |
| US-4610984-A | CEREBRAL INSUFFICIENCY | CASSELLA AKTIENGESELLSCHAFT (DE) | 1986-09-09 | — | — | US | disclosed |
| EP-0123977-A1 | Substituted piperazin-1-yl-acetic-acid amides, process for their preparation and their use | CASSELLA Aktiengesellschaft (DE) | 1984-11-07 | — | — | EP | disclosed |
| US-3933802-A | New sulphamoylbenzoic acid amides | CIBA-GEIGY CORPORATION (US) | 1976-01-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260078219-A1 | Polymer Nanoaggregate Pharmaceutical Composition and Use Thereof | HAO2, HRH1, PHB1 | POLB 282/4885SMN1; SMN2 2178/4885LMNA 1643/4885 |
| US-12544342-B2 | Pharmaceutical composition containing taxane nanoaggregates and use thereof | VHL, LPXN, PLEC | POLB 378/4885SMN1; SMN2 312/4885LMNA 1557/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.