Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | LGMN | Q99538 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | TSHR | P16473 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17542785 | 1.00 | ALDH1A1 (0.56) | ALDH1A1LGMNMAPTKDM4ETSHR | |
| SCHEMBL17542826 | 0.89 | LGMN (0.59) | ALDH1A1LGMNMAPTKDM4ETSHR | |
| SCHEMBL3436573 | 0.88 | MEN1 (0.61) | ALDH1A1LGMNMAPTKDM4ETSHR | |
| SCHEMBL25031455 | 0.85 | LGMN (0.56) | ALDH1A1LGMNMAPTKDM4ETSHR | |
| SCHEMBL3554337 | 0.85 | LGMN (0.65) | ALDH1A1LGMNMAPTKDM4ETSHR | |
| SCHEMBL11199209 | 0.84 | LGMN (0.55) | ALDH1A1LGMNMAPTKDM4ETSHR | |
| SCHEMBL14804172 | 0.83 | KMT2A (0.56) | ALDH1A1LGMNMAPTKDM4ETSHR | |
| SCHEMBL17305299 | 0.83 | LGMN (0.56) | ALDH1A1LGMNMAPTKDM4ETSHR | |
| SCHEMBL196131 | 0.82 | HPGD (0.61) | ALDH1A1LGMNMAPTKDM4ETSHR | |
| SCHEMBL3435998 | 0.81 | MAPT (0.74) | ALDH1A1LGMNMAPTSMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4076423-A1 | TRPML MODULATORS | Casma Therapeutics, Inc. (US) | 2022-10-26 | — | — | EP | disclosed |