Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 6/20 | 1.00 |
| ▸ | PLA2G5 | P39877 | 3/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.49 |
| ▸ | CES2 | O00748 | 4/20 | 0.48 |
| ▸ | CES1 | P23141 | 4/20 | 0.48 |
| ▸ | FAAH | O00519 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | PPARG | P37231 | 2/20 | 0.47 |
| ▸ | PPARA | Q07869 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30798618 | 1.00 | PLA2G2A (1.00) | PLA2G2APLA2G5SMN1; SMN2TP53PLA2G4A | |
| SCHEMBL2118667 | 0.86 | PLA2G2A (0.76) | PLA2G2APLA2G5SMN1; SMN2PLA2G4ACES2 | |
| SCHEMBL2118676 | 0.86 | PLA2G2A (0.76) | PLA2G2APLA2G5SMN1; SMN2PLA2G4ACES2 | |
| SCHEMBL2119435 | 0.83 | PLA2G2A (0.70) | PLA2G2APLA2G5SMN1; SMN2TP53PLA2G4A | |
| SCHEMBL2119429 | 0.83 | PLA2G2A (0.70) | PLA2G2APLA2G5SMN1; SMN2TP53PLA2G4A | |
| SCHEMBL25192254 | 0.83 | PLA2G2A (0.71) | PLA2G2APLA2G5SMN1; SMN2TP53FAAH | |
| SCHEMBL15697666 | 0.83 | PLA2G2A (0.71) | PLA2G2APLA2G5SMN1; SMN2TP53FAAH | |
| SCHEMBL15649018 | 0.83 | PLA2G2A (0.71) | PLA2G2APLA2G5SMN1; SMN2TP53FAAH | |
| SCHEMBL9666963 | 0.83 | PLA2G2A (0.71) | PLA2G2APLA2G5SMN1; SMN2TP53FAAH | |
| SCHEMBL543200 | 0.83 | PLA2G2A (0.71) | PLA2G2APLA2G5SMN1; SMN2TP53FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4313020-A1 | MANAGING THE ACUTE AND LONG-TERM EFFECTS OF CORONAVIRAL INFECTIONS AND COMPOSITIONS RELATED THERETO | Emory University (US) | 2024-02-07 | — | — | EP | disclosed |
| WO-2022204517-A1 | MANAGING THE ACUTE AND LONG-TERM EFFECTS OF CORONAVIRAL INFECTIONS AND COMPOSITIONS RELATED THERETO | EMORY UNIVERSITY (US) | 2022-09-29 | — | — | WO | disclosed |