Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV4 | Q9HBA0 | 2/20 | 0.53 |
| ▸ | CCR2 | P41597 | 8/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | SLC40A1 | Q9NP59 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | OXTR | P30559 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1029355 | 1.00 | TRPV4 (0.53) | TRPV4CCR2ALDH1A1L3MBTL1SLC40A1 | |
| SCHEMBL533050 | 0.84 | TRPV4 (0.50) | TRPV4CCR2ALDH1A1L3MBTL1 | |
| SCHEMBL13343225 | 0.83 | CCR2 (0.51) | TRPV4CCR2ALDH1A1L3MBTL1SLC40A1 | |
| SCHEMBL29009817 | 0.81 | CCR2 (0.50) | TRPV4CCR2ALDH1A1L3MBTL1SLC40A1 | |
| SCHEMBL2774927 | 0.81 | CCR2 (0.50) | CCR2ALDH1A1L3MBTL1SLC40A1 | |
| SCHEMBL12560662 | 0.81 | CCR2 (0.68) | TRPV4CCR2ALDH1A1L3MBTL1SLC40A1 | |
| SCHEMBL29899701 | 0.80 | AKR1B1 (0.46) | TRPV4CCR2ALDH1A1PKMPOLB | |
| SCHEMBL113810 | 0.80 | AKR1B1 (0.46) | TRPV4CCR2ALDH1A1PKMPOLB | |
| Hydrochloric Acid SCHEMBL28031219 | 0.79 | CCR2 (0.49) | TRPV4CCR2ALDH1A1L3MBTL1SLC40A1 | |
| Hydrochloric Acid SCHEMBL7003803 | 0.78 | AKR1B1 (0.45) | TRPV4CCR2ALDH1A1PKMPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4587437-A1 | CYCLIC SULFONAMIDE RIBONUCLEOTIDE REDUCTASE (RNR) INHIBITORS AND USES THEREOF | Boundless Bio, Inc. (US) | 2025-07-23 | — | — | EP | disclosed |
| WO-2024059563-A1 | CYCLIC SULFONAMIDE RIBONUCLEOTIDE REDUCTASE (RNR) INHIBITORS AND USES THEREOF | BOUNDLESS BIO, INC. (US) | 2024-03-21 | — | — | WO | disclosed |
| EP-4061124-A1 | TRPV4 RECEPTOR LIGANDS | University of Utah Research Foundation (US) | 2022-09-28 | — | — | EP | disclosed |