SCHEMBL29948993

SCHEMBL29948993

Cc1nc(Cl)cnc1C(=O)O

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.47
MEN1 O00255 2/20 0.47
TDP1 Q9NUW8 1/20 0.44
ALDH1A1 P00352 4/20 0.40
MAPK1 P28482 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
NAPRT Q6XQN6 1/20 0.38
SIRT6 Q8N6T7 1/20 0.38
ATM Q13315 1/20 0.37
HPGD P15428 2/20 0.37
HCAR2 Q8TDS4 2/20 0.37
TSHR P16473 1/20 0.37
CYP2C9 P11712 1/20 0.36
CYP2C19 P33261 1/20 0.36
HSD17B10 Q99714 1/20 0.36
GRM5 P41594 1/20 0.36
PKM P14618 2/20 0.36
KDM4E B2RXH2 3/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
KMO O15229 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL479985 1.00 KMT2A (0.47) KMT2AMEN1TDP1ALDH1A1MAPK1
SCHEMBL30937725 0.84 ALDH1A1 (0.38) KMT2AMEN1TDP1ALDH1A1MAPK1
SCHEMBL23528889 0.84 KMT2A (0.47) KMT2AMEN1TDP1ALDH1A1MAPK1
SCHEMBL20046666 0.81 MEN1 (0.47) KMT2AMEN1TDP1ALDH1A1MAPK1
SCHEMBL21195742 0.80 KMT2A (0.40) KMT2AMEN1TDP1ALDH1A1MAPK1
SCHEMBL29844624 0.79 NPSR1 (0.47) ALDH1A1MAPK1SMN1; SMN2ATMGRM5
SCHEMBL361753 0.79 NPSR1 (0.47) ALDH1A1MAPK1SMN1; SMN2ATMGRM5
SCHEMBL1615193 0.79 MEN1 (0.46) KMT2AMEN1TDP1ALDH1A1MAPK1
SCHEMBL7422568 0.79 HPGD (0.39) KMT2AMEN1TDP1ALDH1A1MAPK1
SCHEMBL30112052 0.79 HPGD (0.39) KMT2AMEN1TDP1ALDH1A1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025072451-A1 RAS-PI3K INHIBITORS FOR THE TREATMENT OF CANCER AND IMMUNOLOGICAL DISEASES VIVIDION THERAPEUTICS, INC. (US) 2025-04-03 WO disclosed
CN-119072474-A Heterocyclic GLP-1 agonists 加舒布鲁姆生物公司 2024-12-03 CN disclosed
EP-4077286-A1 ISOXAZOLINE DERIVATIVES AS PESTICIDES Elanco Tiergesundheit AG (CH) 2022-10-26 EP disclosed