Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | GRM5 | P41594 | 3/20 | 0.39 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.38 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 2/20 | 0.36 |
| ▸ | KMO | O15229 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29948993 | 0.84 | KMT2A (0.47) | KMT2AMEN1TDP1ALDH1A1MAPK1 | |
| SCHEMBL479985 | 0.84 | KMT2A (0.47) | KMT2AMEN1TDP1ALDH1A1MAPK1 | |
| SCHEMBL2253990 | 0.82 | SIRT6 (0.46) | KMT2AMEN1ALDH1A1GRM5SIRT6 | |
| SCHEMBL20046666 | 0.81 | MEN1 (0.47) | KMT2AMEN1TDP1ALDH1A1MAPK1 | |
| SCHEMBL361702 | 0.79 | NPSR1 (0.47) | ALDH1A1MAPK1SMN1; SMN2GRM5KDM4E | |
| SCHEMBL2408636 | 0.79 | KDM4E (0.40) | KMT2AMEN1TDP1ALDH1A1MAPK1 | |
| SCHEMBL6377192 | 0.79 | MEN1 (0.46) | KMT2AMEN1TDP1ALDH1A1MAPK1 | |
| SCHEMBL10335107 | 0.78 | ALOX15 (0.46) | KMT2AMEN1TDP1ALDH1A1MAPK1 | |
| SCHEMBL2407807 | 0.77 | ALDH1A1 (0.51) | KMT2AMEN1ALDH1A1MAPK1KDM4E | |
| SCHEMBL28504710 | 0.76 | KDM4E (0.38) | KMT2AMEN1TDP1ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260070879-A1 | ISOXAZOLINE DERIVATIVES | ELANCO TIERGESUNDHEIT AG (CH) | 2026-03-12 | — | — | US | disclosed |
| US-12497370-B2 | Isoxazoline derivatives | ELANCO TIERGESUNDHEIT AG (CH) | 2025-12-16 | — | — | US | disclosed |
| CN-120004816-A | Isoxazoline derivatives | 礼蓝动物保健有限公司 | 2025-05-16 | — | — | CN | disclosed |
| US-20250145596-A1 | HETEROCYCLIC GLP-1 AGONISTS | GASHERBRUM BIO, INC. | 2025-05-08 | — | — | US | disclosed |
| CN-115210221-B | Isoxazoline derivatives as pesticides | 礼蓝动物保健有限公司 | 2025-03-18 | — | — | CN | disclosed |
| EP-4476213-A1 | HETEROCYCLIC GLP-1 AGONISTS | Gasherbrum Bio, Inc. (US) | 2024-12-18 | — | — | EP | disclosed |
| CN-119072474-A | Heterocyclic GLP-1 agonists | 加舒布鲁姆生物公司 | 2024-12-03 | — | — | CN | disclosed |
| US-20240124431-A1 | 2,3-DIHYDRO-4H-BENZO[B][1,4]OXAZIN-4-YL)(5-(PHENYL)-PYRIDIN-3-YL)METHANONE DERIVATIVES AND SIMILAR COMPOUNDS AS CYP11A1 INHIBITORS FOR THE TREATMENT OF PROSTATE CANCER | ORION CORPORATION (FI) | 2024-04-18 | — | — | US | disclosed |
| US-11760762-B2 | Thienopyranones and furanopyranones as kinase, bromodomain, and checkpoint inhibitors | SIGNALRX PHARMACEUTICALS, INC. (US) | 2023-09-19 | — | — | US | disclosed |
| WO-2023151575-A1 | HETEROCYCLIC GLP-1 AGONISTS | GASHERBRUM BIO INC. (US) | 2023-08-17 | — | — | WO | disclosed |
| EP-4077286-A1 | ISOXAZOLINE DERIVATIVES AS PESTICIDES | Elanco Tiergesundheit AG (CH) | 2022-10-26 | — | — | EP | disclosed |
| CN-115210221-A | Isoxazoline derivatives as pesticides | 礼蓝动物保健有限公司 | 2022-10-18 | — | — | CN | disclosed |
| US-20210188789-A1 | ISOXAZOLINE DERIVATIVES | ELANCO TIERGESUNDHEIT AG | 2021-06-24 | — | — | US | disclosed |
| WO-2021127188-A1 | ISOXAZOLINE DERIVATIVES AS PESTICIDES | ELANCO TIERGESUNDHEIT AG (CH) | 2021-06-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11760762-B2 | Thienopyranones and furanopyranones as kinase, bromodomain, and checkpoint inhibitors | CDK1, CDKN1A, CDKL1 | KMT2A 1487/4885MEN1 750/4885TDP1 609/4885 |
| US-12497370-B2 | Isoxazoline derivatives | CYP3A7, CYP4X1, CYP2A7 | KMT2A 1360/4885MEN1 4188/4885TDP1 1915/4885 |
| US-20260070879-A1 | ISOXAZOLINE DERIVATIVES | CHRM1, CBR3, AFF1 | KMT2A 1987/4885MEN1 1644/4885TDP1 2994/4885 |
| US-20240124431-A1 | 2,3-DIHYDRO-4H-BENZO[B][1,4]OXAZIN-4-YL)(5-(PHENYL)-PYRIDIN-3-YL)METHANONE DERIVATIVES AND SIMILAR COMPOUNDS AS CYP11A1 INHIBITORS FOR THE TREATMENT OF PROSTATE CANCER | CYP11B1, CYP11B2, SRD5A1 | KMT2A 2136/4885MEN1 1386/4885TDP1 3108/4885 |
| US-20250145596-A1 | HETEROCYCLIC GLP-1 AGONISTS | GLP1R, GIPR, GCGR | KMT2A 3661/4885MEN1 425/4885TDP1 2997/4885 |
| US-20210188789-A1 | ISOXAZOLINE DERIVATIVES | CYP3A7, CYP4X1, SIRT7 | KMT2A 1656/4885MEN1 4136/4885TDP1 1807/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.