Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | EGLN1 | Q9GZT9 | 6/20 | 0.33 |
| ▸ | CFTR | P13569 | 3/20 | 0.33 |
| ▸ | VEGFA | P15692 | 2/20 | 0.33 |
| ▸ | FLT1 | P17948 | 2/20 | 0.33 |
| ▸ | EGLN3 | Q9H6Z9 | 2/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.32 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.32 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23528932 | 1.00 | LMNA (0.41) | LMNAKDM4EGAAPOLBL3MBTL1 | |
| SCHEMBL29948937 | 0.84 | KDM4E (0.41) | LMNAKDM4EGAAEGLN1CFTR | |
| SCHEMBL23528918 | 0.84 | KDM4E (0.41) | LMNAKDM4EGAAEGLN1CFTR | |
| SCHEMBL29948802 | 0.82 | KDM4E (0.40) | LMNAKDM4EGAAPOLBL3MBTL1 | |
| SCHEMBL23528868 | 0.82 | KDM4E (0.40) | LMNAKDM4EGAAPOLBL3MBTL1 | |
| SCHEMBL23528926 | 0.82 | KDM4E (0.40) | LMNAKDM4EGAAL3MBTL1EGLN1 | |
| SCHEMBL23528930 | 0.81 | KDM4E (0.41) | LMNAKDM4EGAAPOLBL3MBTL1 | |
| SCHEMBL28863529 | 0.80 | EGLN1 (0.33) | L3MBTL1EGLN1VEGFAFLT1EGLN3 | |
| SCHEMBL23528927 | 0.79 | KDM4E (0.38) | LMNAKDM4EGAAEGLN1CFTR | |
| SCHEMBL23528864 | 0.77 | KDM4E (0.41) | LMNAKDM4EGAAPOLBL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4077286-A1 | ISOXAZOLINE DERIVATIVES AS PESTICIDES | Elanco Tiergesundheit AG (CH) | 2022-10-26 | — | — | EP | disclosed |