Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK5 | Q00535 | 13/20 | 0.67 |
| ▸ | CDK5R1 | Q15078 | 13/20 | 0.67 |
| ▸ | CCNT1 | O60563 | 10/20 | 0.67 |
| ▸ | CDK9 | P50750 | 10/20 | 0.67 |
| ▸ | CCNA2 | P20248 | 9/20 | 0.67 |
| ▸ | CDK2 | P24941 | 9/20 | 0.67 |
| ▸ | CCNA1 | P78396 | 9/20 | 0.67 |
| ▸ | ROCK1 | Q13464 | 5/20 | 0.57 |
| ▸ | CDC42BPB | Q9Y5S2 | 5/20 | 0.57 |
| ▸ | ROCK2 | O75116 | 4/20 | 0.53 |
| ▸ | CDC42BPA | Q5VT25 | 2/20 | 0.53 |
| ▸ | HTR1A | P08908 | 2/20 | 0.49 |
| ▸ | HTR2B | P41595 | 2/20 | 0.49 |
| ▸ | HTR7 | P34969 | 1/20 | 0.49 |
| ▸ | HTR5A | P47898 | 1/20 | 0.49 |
| ▸ | PDPK1 | O15530 | 2/20 | 0.49 |
| ▸ | GSK3B | P49841 | 4/20 | 0.46 |
| ▸ | CLK1 | P49759 | 2/20 | 0.46 |
| ▸ | CCNB2 | O95067 | 2/20 | 0.46 |
| ▸ | CDK1 | P06493 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2996728 | 0.99 | CDK5 (0.65) | CDK5CDK5R1CCNT1CDK9CCNA2 | |
| SCHEMBL2998000 | 0.99 | CDK5 (0.65) | CDK5CDK5R1CCNT1CDK9CCNA2 | |
| SCHEMBL30093657 | 0.91 | ROCK1 (0.64) | CDK5CDK5R1CCNT1CDK9CCNA2 | |
| SCHEMBL2989444 | 0.83 | CCNT1 (0.67) | CDK5CDK5R1CCNT1CDK9CCNA2 | |
| Meriolin 3 SCHEMBL29489951 | 0.80 | CCNT1 (1.00) | CDK5CDK5R1CCNT1CDK9CCNA2 | |
| Meriolin 3 SCHEMBL2996575 | 0.80 | CCNT1 (1.00) | CDK5CDK5R1CCNT1CDK9CCNA2 | |
| SCHEMBL30093757 | 0.80 | CDK5 (0.61) | CDK5CDK5R1CCNT1CDK9CCNA2 | |
| SCHEMBL2239857 | 0.80 | CDK5 (0.58) | CDK5CDK5R1CCNT1CDK9CCNA2 | |
| SCHEMBL27835141 | 0.80 | CDK5 (0.61) | CDK5CDK5R1CCNT1CDK9CCNA2 | |
| Meriolin 4 SCHEMBL31061625 | 0.78 | CDK5 (1.00) | CDK5CDK5R1CCNT1CDK9CCNA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2125803-B1 | PYRROLO[2,3-B]PYRIDINE COMPOUNDS, AZAINDOLE COMPOUNDS USED FOR SYNTHESIZING SAID PYRROLO[2,3-B]PYRIDINE COMPOUNDS, METHODS FOR THE PRODUCTION THEREOF, AND USES THEREOF | CENTRE NAT RECH SCIENT (FR) | 2013-04-10 | — | — | EP | disclosed |
| US-20100184790-A1 | PYRROLO[2,3-B]PYRIDINE COMPOUNDS, AZAINDOLE COMPOUNDS USED FOR SYNTHESIZING SAID PYRROLO[2,3-B]PYRIDINE COMPOUNDS, METHODS FOR THE PRODUCTION THEREOF, AND USES THEREOF | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2010-07-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100184790-A1 | PYRROLO[2,3-B]PYRIDINE COMPOUNDS, AZAINDOLE COMPOUNDS USED FOR SYNTHESIZING SAID PYRROLO[2,3-B]PYRIDINE COMPOUNDS, METHODS FOR THE PRODUCTION THEREOF, AND USES THEREOF | BAD, PPOX, CASP3 | CDK5 15/4885CDK5R1 64/4885CCNT1 1121/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.