Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K5 | Q99683 | 13/20 | 0.38 |
| ▸ | GRM5 | P41594 | 7/20 | 0.33 |
| ▸ | GRM1 | Q13255 | 6/20 | 0.33 |
| ▸ | MAP3K6 | O95382 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29949153 | 0.83 | NOS3 (0.39) | MAP3K5GRM5GRM1 | |
| SCHEMBL28848832 | 0.77 | MAP3K5 (0.40) | MAP3K5GRM5GRM1MAP3K6 | |
| SCHEMBL29949198 | 0.76 | DHFR (0.40) | MAP3K5GRM5 | |
| SCHEMBL29949085 | 0.74 | MAP3K5 (0.41) | MAP3K5GRM5GRM1 | |
| SCHEMBL28391289 | 0.72 | MAP3K5 (0.53) | MAP3K5MAP3K6 | |
| SCHEMBL29978259 | 0.72 | MAP3K5 (0.53) | MAP3K5MAP3K6 | |
| SCHEMBL29948962 | 0.71 | MAP3K5 (0.42) | MAP3K5 | |
| SCHEMBL15811865 | 0.71 | MAP3K5 (0.42) | MAP3K5 | |
| SCHEMBL28848720 | 0.71 | MAP3K5 (0.42) | MAP3K5 | |
| SCHEMBL18027905 | 0.70 | MAP3K5 (0.55) | MAP3K5MAP3K6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110036005-B | Amide derivatives and their use in medicine | 广东东阳光药业有限公司 | 2022-09-27 | — | — | CN | disclosed |