Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN1A | P35498 | 1/20 | 0.33 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.33 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.33 |
| ▸ | IDH1 | O75874 | 3/20 | 0.33 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.33 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.32 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.32 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.32 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.32 |
| ▸ | KRAS | P01116 | 2/20 | 0.30 |
| ▸ | SOS1 | Q07889 | 2/20 | 0.30 |
| ▸ | CD44 | P16070 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26965612 | 1.00 | SCN1A (0.33) | SCN1ASCN5ASCN8AIDH1FFAR2 | |
| SCHEMBL26965607 | 0.73 | HSD17B10 (0.36) | SCN1ASCN5ASCN8AIDH1 | |
| SCHEMBL15836949 | 0.69 | — | — | |
| SCHEMBL26965586 | 0.68 | EGFR (0.32) | CSNK2A2CSNK2BCSNK2A1CSNK2A3 | |
| SCHEMBL29949337 | 0.68 | EGFR (0.32) | CSNK2A2CSNK2BCSNK2A1CSNK2A3 | |
| SCHEMBL104522 | 0.64 | CYP3A4 (0.48) | CD44 | |
| SCHEMBL29407112 | 0.64 | CYP3A4 (0.48) | CD44 | |
| SCHEMBL3482836 | 0.64 | CD44 (0.48) | CD44 | |
| SCHEMBL10503258 | 0.63 | CYP3A4 (0.48) | CD44 | |
| SCHEMBL23500821 | 0.62 | CXCR4 (0.39) | CD44 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117561247-A | Novel potassium channel inhibitors | 阿塞西翁制药公司 | 2024-02-13 | — | — | CN | disclosed |
| EP-4313973-A1 | NOVEL POTASSIUM CHANNEL INHIBITORS | Acesion Pharma ApS (DK) | 2024-02-07 | — | — | EP | disclosed |
| WO-2022200162-A1 | NOVEL POTASSIUM CHANNEL INHIBITORS | ACECION PHARMA APS (DK) | 2022-09-29 | — | — | WO | disclosed |