SCHEMBL29949337

SCHEMBL29949337

Nc1cccc(CNc2ncco2)c1N

nearest known ligand 0.32

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
EGFR P00533 2/20 0.32
FLT4 P35916 2/20 0.31
CYP1A2 P05177 1/20 0.31
RXRA P19793 1/20 0.31
GRIN1 Q05586 1/20 0.31
GRIN2B Q13224 1/20 0.31
IGF1R P08069 1/20 0.30
KDR P35968 1/20 0.30
CSNK2A2 P19784 1/20 0.30
CSNK2B P67870 1/20 0.30
CSNK2A1 P68400 1/20 0.30
CSNK2A3 Q8NEV1 1/20 0.30
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26965586 1.00 EGFR (0.32) EGFRFLT4CYP1A2RXRAGRIN1
SCHEMBL26965537 0.75 CD44 (0.34) EGFRMEN1KMT2A
SCHEMBL29949172 0.75 CD44 (0.34) EGFRMEN1KMT2A
SCHEMBL26965595 0.72 HDAC4 (0.46) CSNK2A2CSNK2BCSNK2A1CSNK2A3
SCHEMBL29949182 0.72 HDAC4 (0.46) CSNK2A2CSNK2BCSNK2A1CSNK2A3
SCHEMBL26965615 0.71 HSD17B10 (0.37) MEN1KMT2A
SCHEMBL29949208 0.71 BACE1 (0.35) MEN1KMT2A
SCHEMBL26965554 0.71 BACE1 (0.35) MEN1KMT2A
SCHEMBL7046408 0.70 FABP1 (0.50) EGFRFLT4CYP1A2IGF1RKDR
SCHEMBL29949289 0.68 SCN1A (0.33) CSNK2A2CSNK2BCSNK2A1CSNK2A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117561247-A Novel potassium channel inhibitors 阿塞西翁制药公司 2024-02-13 CN disclosed
EP-4313973-A1 NOVEL POTASSIUM CHANNEL INHIBITORS Acesion Pharma ApS (DK) 2024-02-07 EP disclosed
WO-2022200162-A1 NOVEL POTASSIUM CHANNEL INHIBITORS ACECION PHARMA APS (DK) 2022-09-29 WO disclosed