Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 5/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | PNMT | P11086 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | CD44 | P16070 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.36 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.36 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29407112 | 0.83 | CYP3A4 (0.48) | CYP3A4CYP1A2CYP2D6NFKB1PNMT | |
| SCHEMBL3482836 | 0.83 | CD44 (0.48) | CYP3A4CYP1A2CYP2D6NFKB1PNMT | |
| SCHEMBL104522 | 0.83 | CYP3A4 (0.48) | CYP3A4CYP1A2CYP2D6NFKB1PNMT | |
| SCHEMBL6201553 | 0.82 | CYP3A4 (0.48) | CYP3A4CYP1A2CYP2D6NFKB1PNMT | |
| SCHEMBL1061130 | 0.82 | CYP3A4 (0.48) | CYP3A4CYP1A2CYP2D6NFKB1PNMT | |
| SCHEMBL16512108 | 0.82 | CYP3A4 (0.48) | CYP3A4CYP1A2CYP2D6NFKB1PNMT | |
| Hydrochloric Acid SCHEMBL28495226 | 0.80 | ALDH1A1 (0.50) | CYP3A4CYP1A2CYP2D6NFKB1PNMT | |
| SCHEMBL18341001 | 0.79 | CD44 (0.44) | CYP3A4CYP1A2CYP2D6NFKB1PNMT | |
| SCHEMBL992768 | 0.79 | CD44 (0.44) | CYP3A4CYP1A2CYP2D6NFKB1PNMT | |
| SCHEMBL24440433 | 0.77 | GABRA1 (0.48) | CYP3A4CYP1A2CYP2D6NFKB1PNMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0288867-A3 | AMINOPHENYL ETHYL AMINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS PERFORMANCE PROMOTORS | BAYER AG (DE) | 1989-11-15 | — | — | EP | disclosed |
| EP-0288867-A2 | Aminophenyl ethyl amine derivatives, process for their preparation and their use as performance promotors | BAYER AG (DE) | 1988-11-02 | — | — | EP | disclosed |
| EP-0225600-A2 | Process for increasing the efficiency of useful animals, new aminophenylethylamine derivatives, and their preparation | BAYER AG (DE) | 1987-06-16 | — | — | EP | disclosed |
| EP-0119446-A3 | GROWTH PROMOTING AMINOPHENYLETHYL AMINE DERIVATIVES | BAYER AG (DE) | 1985-03-27 | — | — | EP | disclosed |
| EP-0119446-A2 | Growth promoting aminophenylethyl amine derivatives | BAYER AG (DE) | 1984-09-26 | — | — | EP | disclosed |