Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.50 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.46 |
| ▸ | NCEH1 | Q6PIU2 | 5/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.38 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.38 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11503575 | 1.00 | POLB (0.56) | POLBALDH1A1HSD17B10CYP2A6TSHR | |
| SCHEMBL22500012 | 0.77 | POLB (0.47) | POLBALDH1A1HSD17B10CYP2A6TSHR | |
| SCHEMBL1298247 | 0.75 | ALDH1A1 (0.55) | POLBALDH1A1HSD17B10CYP2A6TSHR | |
| SCHEMBL1187756 | 0.75 | POLB (0.60) | POLBALDH1A1HSD17B10CYP2A6TSHR | |
| SCHEMBL1913838 | 0.71 | POLB (0.56) | POLBALDH1A1HSD17B10CYP2A6TSHR | |
| SCHEMBL15453239 | 0.71 | ALDH1A1 (0.50) | POLBALDH1A1HSD17B10CYP2A6TSHR | |
| SCHEMBL49630 | 0.71 | POLB (1.00) | POLBALDH1A1HSD17B10CYP2A6TSHR | |
| SCHEMBL9720422 | 0.71 | CYP2A6 (0.60) | POLBALDH1A1HSD17B10CYP2A6TSHR | |
| SCHEMBL7364085 | 0.71 | POLB (0.56) | POLBALDH1A1HSD17B10CYP2A6TSHR | |
| SCHEMBL5858906 | 0.71 | CYP2A6 (0.60) | ALDH1A1HSD17B10CYP2A6TSHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4077335-A1 | AROMATIC COMPOUNDS FOR ORGANIC ELECTROLUMINESCENT DEVICES | Merck Patent GmbH (DE) | 2022-10-26 | — | — | EP | disclosed |