SCHEMBL49630

SCHEMBL49630

Oc1ccc2ccccc2c1Br

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 2/20 1.00
PTPN22 Q9Y2R2 1/20 0.60
CYP1A2 P05177 2/20 0.54
HSD17B10 Q99714 2/20 0.54
USP2 O75604 1/20 0.54
PAK1 Q13153 1/20 0.54
CYP2C9 P11712 1/20 0.54
CYP2C19 P33261 1/20 0.54
ALDH1A1 P00352 2/20 0.50
TDP1 Q9NUW8 2/20 0.50
GAA P10253 2/20 0.50
MAPT P10636 2/20 0.50
CYP2A6 P11509 1/20 0.50
TSHR P16473 1/20 0.50
ESR1 P03372 1/20 0.50
ESR2 Q92731 1/20 0.50
HSD17B1 P14061 1/20 0.50
HSD17B2 P37059 1/20 0.50
KDM4E B2RXH2 1/20 0.50
TAAR1 Q96RJ0 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7756493 0.87 POLB (0.75) POLBPTPN22CYP1A2HSD17B10USP2
SCHEMBL28853958 0.80 POLB (0.67) POLBPTPN22CYP1A2HSD17B10USP2
SCHEMBL29362162 0.75 PTPN22 (0.65) POLBPTPN22CYP1A2HSD17B10USP2
SCHEMBL29613822 0.75 PTPN22 (1.00) POLBPTPN22CYP1A2HSD17B10USP2
SCHEMBL28853957 0.75 POLB (0.60) POLBPTPN22MAPTESR1ESR2
SCHEMBL1187756 0.75 POLB (0.60) POLBPTPN22CYP1A2HSD17B10CYP2C9
SCHEMBL15400598 0.75 PTPN22 (0.65) POLBPTPN22CYP1A2HSD17B10USP2
SCHEMBL29027 0.75 PTPN22 (0.65) POLBPTPN22CYP1A2HSD17B10USP2
Hydrochloric Acid SCHEMBL28347175 0.75 PTPN22 (1.00) POLBPTPN22CYP1A2HSD17B10USP2
SCHEMBL28483 0.75 PTPN22 (1.00) POLBPTPN22CYP1A2HSD17B10USP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 803 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3494396-B1 CHEMILUMINESCENT AND FLUORESCENT SUBSTRATE PADS AND USES THEREOF PIERCE BIOTECHNOLOGY INC (US) 2025-06-11 EP claimed
CN-119836122-A Passivation layer, preparation method thereof and perovskite solar cell 天合光能股份有限公司 2025-04-15 CN claimed
US-20250034321-A1 COMPOSITIONS OF EPOXY CURING AGENT INCORPORATING NAPHTHOL AND NAPHTHOL DERIVATIVES EVONIK OPERATIONS GMBH (DE) 2025-01-30 US claimed
CN-118834119-A Method for synthesizing bisphenol compound by catalysis of supported ionic liquid 郑州中科新兴产业技术研究院 2024-10-25 CN claimed
EP-4413058-A1 COMPOSITIONS OF EPOXY CURING AGENT INCORPORATING NAPHTHOL AND NAPHTHOL DERIVATIVES Evonik Operations GmbH (DE) 2024-08-14 EP claimed
CN-118055962-A Epoxy curing agent composition comprising naphthol and naphthol derivative 赢创运营有限公司 2024-05-17 CN claimed
WO-2023057234-A9 COMPOSITIONS OF EPOXY CURING AGENT INCORPORATING NAPHTHOL AND NAPHTHOL DERIVATIVES EVONIK OPERATIONS GMBH (DE) 2024-05-10 WO claimed
CN-113549002-B D-sigma-A configuration compound, synthesis method and application 西安近代化学研究所 2023-12-12 CN claimed
CN-113636971-B D-A spiro framework compound, synthesis method and application 西安近代化学研究所 2023-10-20 CN claimed
WO-2023057234-A1 COMPOSITIONS OF EPOXY CURING AGENT INCORPORATING NAPHTHOL AND NAPHTHOL DERIVATIVES EVONIK OPERATIONS GMBH (DE) 2023-04-13 WO claimed
EP-0488860-B1 Method for the production of polyalkoxylated aromatic compounds RHONE POULENC CHIMIE (FR) 1995-10-11 EP claimed
EP-0653637-A2 Dry elements, test devices, test kits and methods for chemiluminescent detection of analytes using peroxidase labeled reagents EASTMAN KODAK COMPANY (US) 1995-05-17 EP claimed
WO-1994023060-A2 ENHANCEMENT OF CHEMILUMINESCENT REACTIONS BRITISH TECHNOLOGY GROUP LIMITED (GB) 1994-10-13 WO claimed
EP-0210449-B1 PROLONGED CHEMILUMINESCENCE MILES INC. (US) 1993-07-28 EP claimed
US-5182213-A Coupling a Phenylenediamine and a Naphthol MILES INC. (US) 1993-01-26 US claimed
EP-0504663-A1 Peroxidase indicator system for basic media Bayer Corporation (US) 1992-09-23 EP claimed
US-4950588-A DETECTION OF NUCLEIC ACID HYBRIDS, ANTIBODIES ANTIGENS MOLECULAR DIAGNOSTICS, INC. (US) 1990-08-21 US claimed
WO-1990006372-A1 SUBSTRATES FOR PEROXIDASE ASSAYING MICROPROBE CORPORATION (US) 1990-06-14 WO claimed
EP-0210449-A2 Prolonged chemiluminescence MILES INC. (US) 1987-02-04 EP claimed
EP-0116454-A2 Enhanced luminescent or luminometric assay NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) 1984-08-22 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250034321-A1 COMPOSITIONS OF EPOXY CURING AGENT INCORPORATING NAPHTHOL AND NAPHTHOL DERIVATIVES SRM, PNMT, NIT2 POLB 546/4885PTPN22 4686/4885CYP1A2 1220/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.