SCHEMBL29949486

SCHEMBL29949486

COc1ccc(CNc2nc(N3CCCCCC3)nc3c2ncn3C(C)C)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CCNE1 P24864 10/20 0.98
CDK2 P24941 10/20 0.98
CCNE2 O96020 7/20 0.98
TDP1 Q9NUW8 1/20 0.71
CDK1 P06493 6/20 0.70
CDK5 Q00535 3/20 0.65
CDK5R1 Q15078 3/20 0.65
CCNB1 P14635 2/20 0.63
CCNB2 O95067 1/20 0.63
CCNB3 Q8WWL7 1/20 0.63
CCNT1 O60563 1/20 0.61
PDE5A O76074 1/20 0.61
CCNA2 P20248 1/20 0.61
CDK7 P50613 1/20 0.61
CDK9 P50750 1/20 0.61
CCNH P51946 1/20 0.61
MNAT1 P51948 1/20 0.61
PDE4D Q08499 1/20 0.61
PDE10A Q9Y233 1/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30848441 0.85 CCNE1 (0.78) CCNE1CDK2CCNE2TDP1CDK1
Myoseverin SCHEMBL29376276 0.83 TDP1 (1.00) CCNE1CDK2CCNE2TDP1CDK1
Myoseverin SCHEMBL13325947 0.83 TDP1 (1.00) CCNE1CDK2CCNE2TDP1CDK1
SCHEMBL13046772 0.83 CDK1 (1.00) CCNE1CDK2CCNE2CDK1CDK5
SCHEMBL1443236 0.81 TDP1 (0.80) CCNE1CDK2CCNE2TDP1CDK1
SCHEMBL28771424 0.79 CDK2 (0.72) CCNE1CDK2CCNE2CDK1CDK5
SCHEMBL13359693 0.79 TDP1 (0.90) CCNE1CDK2CCNE2TDP1CDK1
SCHEMBL5461238 0.79 TDP1 (0.86) CCNE1CDK2CCNE2TDP1CDK1
SCHEMBL28461067 0.78 CDK2 (0.66) CCNE1CDK2CCNE2CDK1CDK5
SCHEMBL5466080 0.78 TDP1 (0.74) CCNE1CDK2CCNE2TDP1CDK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026106966-A1 SYNTHETIC INTRON SCREENING SYSTEM, COMPONENTS THEREOF, AND METHODS OF USING SAME TO ENRICH FOR BASE EDITING ACTIVITY THE BROAD INSTITUTE, INC. (US) 2026-05-21 WO disclosed
WO-2026103462-A1 HANDOVER METHOD, DEVICE, APPARATUS, AND STORAGE MEDIUM 大唐移动通信设备有限公司 2026-05-21 WO disclosed
CN-122069561-A Switching method, device, apparatus and storage medium 大唐移动通信设备有限公司 2026-05-19 CN disclosed
EP-4679096-A1 BIOMARKERS AND METHOD FOR ESTIMATING BRAIN NEURODEGENERATIVE CONDITION SHIMADZU CORPORATION (JP) 2026-01-14 EP disclosed
EP-4679097-A1 METHOD FOR ESTIMATING BRAIN NEURODEGENERATIVE CONDITION SHIMADZU CORPORATION (JP) 2026-01-14 EP disclosed
JP-7729523-B1 公立大学法人 富山県立大学 2025-08-26 JP disclosed
CN-111936163-B Antisense oligomers for the treatment of conditions and diseases based on nonsense-mediated RNA decay 斯托克制药公司 2025-04-04 CN disclosed
WO-2024185666-A1 BIOMARKERS AND METHOD FOR ESTIMATING BRAIN NEURODEGENERATIVE CONDITION 株式会社島津製作所 2024-09-12 WO disclosed
WO-2024163956-A2 SIGMA RECEPTOR LIGAND COMPOUNDS UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) 2024-08-08 WO disclosed
CN-115865054-A Resettable D trigger with anti-irradiation reinforced scanning structure 中国电子科技集团公司第四十七研究所 2023-03-28 CN disclosed
US-20220401539-A1 Immunotherapy Targeting Tumor Neoantigenic Peptides INSTITUT CURIE (FR) 2022-12-22 US disclosed
CN-115276612-A Scanning structure D trigger with soft error self-repairing function 中国电子科技集团公司第四十七研究所 2022-11-01 CN disclosed