Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 6/20 | 0.44 |
| ▸ | HTR7 | P34969 | 4/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5259729 | 0.87 | DHFR (0.46) | — | |
| SCHEMBL29950001 | 0.84 | TSHR (0.45) | — | |
| SCHEMBL1716008 | 0.84 | CNR2 (0.48) | — | |
| SCHEMBL6689039 | 0.84 | NPC1 (0.45) | — | |
| SCHEMBL5260181 | 0.83 | NPC1 (0.50) | — | |
| SCHEMBL6737897 | 0.77 | CNR2 (0.46) | — | |
| SCHEMBL6235260 | 0.74 | TSHR (0.63) | — | |
| SCHEMBL5309142 | 0.73 | HPGD (0.44) | — | |
| SCHEMBL1522607 | 0.72 | MIF (0.66) | — | |
| SCHEMBL6736819 | 0.72 | DHFR (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108069952-B | Quinolinone compound and application thereof in medicines | 广东东阳光药业有限公司 | 2022-09-27 | — | — | CN | disclosed |