Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.42 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.42 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29949593 | 0.84 | HTR1A (0.44) | — | |
| SCHEMBL5259729 | 0.84 | DHFR (0.46) | TSHR | |
| SCHEMBL6689039 | 0.81 | NPC1 (0.45) | TSHR | |
| SCHEMBL5260181 | 0.80 | NPC1 (0.50) | — | |
| SCHEMBL1716008 | 0.79 | CNR2 (0.48) | — | |
| SCHEMBL6737897 | 0.74 | CNR2 (0.46) | TSHR | |
| SCHEMBL28849138 | 0.72 | GSK3B (0.52) | — | |
| SCHEMBL29950200 | 0.72 | GSK3B (0.52) | — | |
| SCHEMBL3580000 | 0.71 | NOS3 (0.44) | — | |
| SCHEMBL6235260 | 0.71 | TSHR (0.63) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108069952-B | Quinolinone compound and application thereof in medicines | 广东东阳光药业有限公司 | 2022-09-27 | — | — | CN | disclosed |