SCHEMBL29950169

SCHEMBL29950169

O=[N+]([O-])c1cc(O)ccc1-c1ccc(O)cc1[N+](=O)[O-]

nearest known ligand 0.57

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.57
ESR2 Q92731 1/20 0.57
AR P10275 1/20 0.54
MAPT P10636 1/20 0.52
BACE1 P56817 1/20 0.47
ALDH1A1 P00352 2/20 0.47
TSHR P16473 2/20 0.47
ALOX15 P16050 2/20 0.47
GPR35 Q9HC97 4/20 0.46
EGFR P00533 1/20 0.46
MAPK1 P28482 2/20 0.45
KCNMA1 Q12791 1/20 0.45
TP53 P04637 1/20 0.45
HPGD P15428 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
HSD17B10 Q99714 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
HSP90AA1 P07900 2/20 0.43
HSP90AB1 P08238 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6796101 1.00 ESR1 (0.57) ESR1ESR2ARMAPTBACE1
SCHEMBL6801027 0.88 MAPT (0.59) ESR1ESR2ARMAPTBACE1
SCHEMBL99637 0.85 ALDH1A1 (0.61) ESR1ESR2ARMAPTALDH1A1
SCHEMBL29577003 0.84 TSHR (0.56) ESR1ESR2BACE1ALDH1A1TSHR
SCHEMBL213758 0.84 TSHR (0.56) ESR1ESR2BACE1ALDH1A1TSHR
Methane SCHEMBL27823028 0.82 TSHR (0.54) ESR1ESR2BACE1ALDH1A1TSHR
SCHEMBL69947 0.82 MAPK1 (0.67) ESR1ESR2MAPTBACE1ALDH1A1
SCHEMBL6031674 0.82 MAPK1 (0.67) ESR1ESR2MAPTBACE1ALDH1A1
SCHEMBL29502912 0.82 MAPK1 (0.67) ESR1ESR2MAPTBACE1ALDH1A1
SCHEMBL29484216 0.82 MAPT (0.71) ESR1ESR2ARMAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110156613-B Synthetic method of 3, 3-diaminodiphenol hydrochloride 浙江工业大学 2022-09-30 CN claimed