Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | ESR2 | Q92731 | 6/20 | 0.51 |
| ▸ | ESR1 | P03372 | 5/20 | 0.51 |
| ▸ | AR | P10275 | 1/20 | 0.49 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.43 |
| ▸ | PRKACA | P17612 | 1/20 | 0.43 |
| ▸ | CASP6 | P55212 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | BACE1 | P56817 | 1/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL99637 | 0.89 | ALDH1A1 (0.61) | MAPTESR2ESR1ARABCB1 | |
| SCHEMBL29950169 | 0.88 | ESR1 (0.57) | MAPTESR2ESR1ARHSD17B10 | |
| SCHEMBL6796101 | 0.88 | ESR1 (0.57) | MAPTESR2ESR1ARHSD17B10 | |
| SCHEMBL4667166 | 0.87 | ALDH1A1 (0.58) | MAPTALDH1A1TDP1CA12LMNA | |
| SCHEMBL13982830 | 0.86 | MAPT (0.53) | MAPTESR2ESR1ALDH1A1LMNA | |
| SCHEMBL12722617 | 0.86 | TSHR (0.55) | MAPTESR2ESR1ARABCB1 | |
| SCHEMBL29484216 | 0.86 | MAPT (0.71) | MAPTESR2ESR1ARABCB1 | |
| SCHEMBL28244181 | 0.86 | ALDH1A1 (0.56) | MAPTALDH1A1TDP1CA12LMNA | |
| SCHEMBL4667148 | 0.85 | VCAM1 (0.54) | MAPTESR2ESR1ARABCB1 | |
| SCHEMBL6910913 | 0.84 | MAPT (0.51) | MAPTESR2ESR1ARABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6762205-B1 | STEROID SULFATASE INHIBITORS WITHOUT ESTROGENIC SIDE EFFECT ACTION | TEIKOKU HORMONE MFG. CO., LTD. (JP) | 2004-07-13 | — | — | US | disclosed |
| EP-1193250-A1 | PHENYL SULFAMATE DERIVATIVES | Teikoku Hormone Mfg. Co., Ltd. (JP) | 2002-04-03 | — | — | EP | disclosed |