Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.39 |
| ▸ | PDE2A | O00408 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ALDH1A3 | P47895 | 8/20 | 0.35 |
| ▸ | ALDH1A2 | O94788 | 7/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | PI4KA | P42356 | 1/20 | 0.34 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.34 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.34 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | F7 | P08709 | 1/20 | 0.34 |
| ▸ | F3 | P13726 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27028518 | 1.00 | ATAD2 (0.39) | ATAD2PDE2AGAAALDH1A1MEN1 | |
| SCHEMBL20674061 | 0.85 | PI4KA (0.37) | ATAD2PDE2AGAAALDH1A1MEN1 | |
| SCHEMBL20674052 | 0.83 | PDE2A (0.44) | ATAD2PDE2AGAAALDH1A1MEN1 | |
| SCHEMBL31403623 | 0.80 | KDM4E (0.55) | KMT2AKDM4E | |
| SCHEMBL22805376 | 0.75 | PDE2A (0.41) | ATAD2PDE2AGAAALDH1A1MEN1 | |
| SCHEMBL6342897 | 0.75 | PDE2A (0.41) | PDE2AGAAALDH1A1MEN1KMT2A | |
| SCHEMBL30095667 | 0.74 | PDE2A (0.60) | PDE2AGAAALDH1A1MEN1KMT2A | |
| SCHEMBL31194629 | 0.72 | KDM4E (0.39) | GAAALDH1A1POLBPI4KAPI4K2B | |
| SCHEMBL31403751 | 0.72 | KDM4E (0.39) | GAAALDH1A1POLBPI4KAPI4K2B | |
| SCHEMBL15024702 | 0.72 | KDM4E (0.54) | ATAD2ALDH1A1KMT2APOLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4308563-A1 | MODULATORS OF STING (STIMULATOR OF INTERFERON GENES) | Pfizer Inc. (US) | 2024-01-24 | — | — | EP | disclosed |
| CN-117321055-A | Modulators of STING (interferon gene stimulators) | 辉瑞公司 | 2023-12-29 | — | — | CN | disclosed |
| WO-2022195462-A1 | MODULATORS OF STING (STIMULATOR OF INTERFERON GENES) | PFIZER INC. (US) | 2022-09-22 | — | — | WO | disclosed |